Protective effect of ellagic acid against lead-induced reproductive toxicity in male rats (Record no. 17240)
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| fixed length control field | a |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20220730150114.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 220730b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | AIKTC-KRRC |
| Transcribing agency | AIKTC-KRRC |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 17430 |
| Author | Bhattacharjee, Ananya |
| 245 ## - TITLE STATEMENT | |
| Title | Protective effect of ellagic acid against lead-induced reproductive toxicity in male rats |
| 250 ## - EDITION STATEMENT | |
| Volume, Issue number | Vol.16(2), Apr-Jun |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Mandsaur |
| Name of publisher, distributor, etc. | BRNSS Publication Hub. |
| Year | 2022 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Pagination | 198-202p. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Introduction: Infertility affects many couples especially in developing countries and is a reproductive health<br/>problem worldwide. The widespread use of heavy metals like lead has led to manifold rise in the occurrence of<br/>free lead in biological systems and the inert environment. The detrimental effect on male reproductive system<br/>is one of the major evidence of occupational and environmental lead exposure. It has been documented that the<br/>presence of higher amounts of lead in the blood of exposed workers compared to control workers is associated with<br/>reduced volume of ejaculation, decreased total sperm number and motility, and reduction in semen density, as well<br/>as increased percentage of pathological spermatozoa. Materials and Methods: The lead-induced reproductive<br/>toxicity study was carried out in healthy adult male Wister albino rats. Rat doses of ELLAGIC acid (EA) were<br/>selected as 50 mg/kg and 25 mg/kg through oral route. After acclimatization, animals were divided into four<br/>random groups of eight animals in each; received normal saline, lead acetate, and EA high and low doses along with<br/>lead acetate, respectively, for 70 days. Serum was separated by centrifugation for the estimation of testosterone<br/>level by ELISA. Thereafter, the animals were sacrificed; testis was weighed and used for the epididymal sperm<br/>count, motility, and viability and then for preparation of homogenate to estimate antioxidants such as super oxide<br/>dismutase, catalase, and thiobarbituric acid reactive substances. Remaining testis was embedded in formaline<br/>in saline solution (10%) for histological examination. Results, Discussion, and Conclusion: Observed results<br/>suggested dose dependent beneficial effects for EA against lead acetate induced male reproductive toxicity and<br/>it was concluded that EA exhibited dose-dependent protection against lead-induced male reproductive toxicity.<br/><br/><br/>Key words: <br/>Ellagic acid, heavy metal toxicity, lead acetate, male reproductive toxicity |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 4774 |
| Topical term or geographic name entry element | PHARMACOLOGY |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 16053 |
| Co-Author | Kulkarni, Venkatrao H. |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 12164 |
| Co-Author | Habbu, Prasanna V. |
| 773 0# - HOST ITEM ENTRY | |
| Place, publisher, and date of publication | Mandsaur B.R. Nahata Smriti Sansthan |
| Title | International journal of green pharmacy |
| International Standard Serial Number | 0973-8258 |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| URL | https://www.greenpharmacy.info/index.php/ijgp/article/view/3254 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Articles Abstract Database |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection code | Home library | Current library | Shelving location | Date acquired | Total Checkouts | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | Not For Loan | Reference | School of Pharmacy | School of Pharmacy | Archieval Section | 30/07/2022 | 2022-1242 | 30/07/2022 | 30/07/2022 | Articles Abstract Database |