Therapeutic approaches of nanotechnology for epileptic seizures: a comprehensive review of current knowledge (Record no. 17318)
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| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20220825100047.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 220825b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | AIKTC-KRRC |
| Transcribing agency | AIKTC-KRRC |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 17582 |
| Author | Shrivastava, Aman |
| 245 ## - TITLE STATEMENT | |
| Title | Therapeutic approaches of nanotechnology for epileptic seizures: a comprehensive review of current knowledge |
| 250 ## - EDITION STATEMENT | |
| Volume, Issue number | Vol.56(3), Jul-Sep |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Karnataka |
| Name of publisher, distributor, etc. | Association of Pharmaceutical Teachers of India (APTI) |
| Year | 2022 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Pagination | 628-635p. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Epilepsy is a chronic neurological condition in which several neurotransmitters act like<br/>neuromodulators. The symptoms of epilepsy are caused by abnormal electrical discharges<br/>in a group of neurons in the hippocampus region of the brain. This can also affect electrical<br/>impulse generation, either in the focal area or in the hippocampus region of the brain. This<br/>review aimed to develop a better understanding of the transportation of nanoparticles<br/>across the blood-brain barrier and how to enhance the delivery of the drug in epileptic<br/>conditions by the utilization of nanomaterials. A few clinical studies have reported that<br/>antiepileptic drugs are generally used for the treatment of epilepsy by decreasing the<br/>frequency and intensity of seizures or preventing tissue damage in the brain. In long-<br/>term therapy, antiepileptic drugs are primarily administered via the oral route, but they<br/>are not always beneficial. Therefore, intravenous routes are especially used in serious<br/>epileptic conditions. In this review, we discussed the drug delivery study of antiepileptic<br/>drugs that are used in the form of nanoparticles that can easily be transported across the<br/>blood-brain barrier. Besides, the nanoparticles can easily cross the blood-brain barrier and<br/>increase the uptake into the target cells. Drug absorption into the brain is substantially<br/>limited by some factors, especially in the blood-brain barrier, which affects the potency<br/>of antiepileptic drugs to reach and remain inside the brain. Novel drug delivery systems<br/>have already been studied in many clinical trials to enhance the therapeutic efficacy of<br/>antiepileptic drugs in epileptic conditions. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 4639 |
| Topical term or geographic name entry element | PHARMACEUTICS |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 17583 |
| Co-Author | Gupta, Jeetendra K. |
| 773 0# - HOST ITEM ENTRY | |
| International Standard Serial Number | 0019-5464 |
| Title | Indian journal of pharmaceutical education and research |
| Place, publisher, and date of publication | Bengluru Association of Pharmaceutical Teachers of India (APTI) |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| URL | https://ijper.org/sites/default/files/IndJPhaEdRes-56-3-628_0.pdf |
| Link text | Click here |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Articles Abstract Database |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Home library | Current library | Shelving location | Date acquired | Total Checkouts | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | School of Pharmacy | School of Pharmacy | Archieval Section | 25/08/2022 | 2022-1362 | 25/08/2022 | 25/08/2022 | Articles Abstract Database |