Thiazoles: a retrospective study on synthesis, structure-activity relationship and therapeutic significance (Record no. 17320)

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003 - CONTROL NUMBER IDENTIFIER
control field OSt
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20220825105404.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 220825b xxu||||| |||| 00| 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency AIKTC-KRRC
Transcribing agency AIKTC-KRRC
100 ## - MAIN ENTRY--PERSONAL NAME
9 (RLIN) 17585
Author Sharma, Shivkant
245 ## - TITLE STATEMENT
Title Thiazoles: a retrospective study on synthesis, structure-activity relationship and therapeutic significance
250 ## - EDITION STATEMENT
Volume, Issue number Vol.56(3), Jul-Aug
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Karnataka
Name of publisher, distributor, etc. Association of Pharmaceutical Teachers of India (APTI)
Year 2022
300 ## - PHYSICAL DESCRIPTION
Pagination 646-666p.
520 ## - SUMMARY, ETC.
Summary, etc. Thiazole or 1,3-thiazole is a distinct heterocyclic compound which incorporates sulphur<br/>and nitrogen atoms. It is a vital framework present in numerous pharmacologically<br/>active compounds, be it of natural origin or of synthetic nature. Many thiazoles having<br/>antitumor and antiviral activities, originate from microbes and marine organisms. A variety<br/>of synthetic drugs, having thiazole group, like antimicrobial sulfathiazole, antibiotic<br/>penicillin, antidepressant pramipexole, antineoplastic agent bleomycin, antiretroviral drug<br/>ritonavir, histamine H 2 receptor antagonist nizatidine, anti-inflammatory drug meloxicam,<br/>antifungal stilbene derivatives have been in the markets for quite some time. Hofmann and<br/>Hantzsch laid the groundwork for further development in the field of thiazole chemistry.<br/>The interaction of α-haloketones or α-halogenaldehyde and thioamide to obtain thiazoles<br/>is beautifully described by Hantzsch. Various studies have reported methods for the<br/>synthesis of the thiazoles; thioforamide, thiourea, α-thiocyanotoketones, and vinyl<br/>bromide have been extensively employed to synthesize thiazoles. The thiazoles have<br/>immense potential and this study tries to enlighten the crucial role of thiazoles for the<br/>betterment of society. The review provides different directions in the synthesis of novel<br/>thiazoles and also reveals diverse targets for augmentation in the field of designing of<br/>novel thiazoles.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
9 (RLIN) 4639
Topical term or geographic name entry element PHARMACEUTICS
700 ## - ADDED ENTRY--PERSONAL NAME
9 (RLIN) 17586
Co-Author Devgun, Manish
773 0# - HOST ITEM ENTRY
Title Indian journal of pharmaceutical education and research
International Standard Serial Number 0019-5464
Place, publisher, and date of publication Bengluru Association of Pharmaceutical Teachers of India (APTI)
856 ## - ELECTRONIC LOCATION AND ACCESS
URL https://www.ijper.org/sites/default/files/IndJPhaEdRes-56-3-646.pdf
Link text Click here
942 ## - ADDED ENTRY ELEMENTS (KOHA)
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Koha item type Articles Abstract Database
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    Dewey Decimal Classification     School of Pharmacy School of Pharmacy Archieval Section 25/08/2022   2022-1367 25/08/2022 25/08/2022 Articles Abstract Database
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