Potential of ocimum sanctum to inhibit the growth of pseudomonas aeruginosa, a disease-causing micro-organism (Record no. 17344)

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003 - CONTROL NUMBER IDENTIFIER
control field OSt
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20220826145440.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 220826b xxu||||| |||| 00| 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency AIKTC-KRRC
Transcribing agency AIKTC-KRRC
100 ## - MAIN ENTRY--PERSONAL NAME
9 (RLIN) 17626
Author Yadav, Raj Narayan
245 ## - TITLE STATEMENT
Title Potential of ocimum sanctum to inhibit the growth of pseudomonas aeruginosa, a disease-causing micro-organism
250 ## - EDITION STATEMENT
Volume, Issue number Vol.56(3) Jul-Sep
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Karnataka
Name of publisher, distributor, etc. Association of Pharmaceutical Teachers of India (APTI)
Year 2022
300 ## - PHYSICAL DESCRIPTION
Pagination 816-821p.
520 ## - SUMMARY, ETC.
Summary, etc. Aim and Objectives: Plants are a good source of secondary metabolites, which have huge<br/>potential to kill micro-organisms. The present study aimed to evaluate the antimicrobial<br/>activity of<br/>Ocimum sanctum ethanol extract against drug-resistant and drug-sensitive<br/>strains of<br/>Pseudomonas aeruginosa (<br/>P. aeruginosa). Materials and Methods: A total of<br/>119 strains of<br/>P. aeruginosa, 92 multidrug-resistant (MDR) and 27 pan sensitive strains<br/>were included in the study, which were isolated from different human clinical samples.<br/>Ocimum sanctum crude leaves extract was prepared with the standard “cold extraction<br/>method”. The susceptibility agar dilution plates were made by mixing molten Mueller-<br/>Hinton Agar (MHA) media with plant extract in different quantities to get the final extract<br/>concentration of 0.2%, 0.1% and 0.05%. These plates were used for determining the<br/>sensitive/ resistance nature of all strains of<br/>P. aeruginosa against plant extract. Results:<br/>Among 92 MDR strains in MHA plates with 0.05% of plant extract, 59 strains were<br/>sensitive and 33 were resistant. The same MDR strains in MHA plate with 0.1% of the<br/>extract showed somewhat similar trends, 61 sensitive and 31 resistant. Whereas with<br/>0.2% of the extract, 67 strains were sensitive, 11 showed resistance while 14 showed<br/>discrete colonies. Among 27 pan sensitive strains at 0.05% concentration, there was<br/>complete growth inhibition in 23, while discrete colonies were observed in 4, though, at<br/>0.1% and 0.2%, all strains were found as sensitive. Conclusion: Analysis of the present<br/>study showed that<br/>Ocimum sanctum extract possess compounds with antimicrobial<br/>properties against commonly used isolates of<br/>Pseudomonas aeruginosa strains.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
9 (RLIN) 4639
Topical term or geographic name entry element PHARMACEUTICS
700 ## - ADDED ENTRY--PERSONAL NAME
9 (RLIN) 17627
Co-Author Kayesth, Sunil
773 0# - HOST ITEM ENTRY
Place, publisher, and date of publication Bengluru Association of Pharmaceutical Teachers of India (APTI)
International Standard Serial Number 0019-5464
Title Indian journal of pharmaceutical education and research
856 ## - ELECTRONIC LOCATION AND ACCESS
URL https://www.ijper.org/sites/default/files/IndJPhaEdRes-56-3-816.pdf
Link text Click here
942 ## - ADDED ENTRY ELEMENTS (KOHA)
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Koha item type Articles Abstract Database
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    Dewey Decimal Classification     School of Pharmacy School of Pharmacy Archieval Section 26/08/2022   2022-1394 26/08/2022 26/08/2022 Articles Abstract Database
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