Estimation of antioxidant and cytotoxicity activities of extracts obtained from the leaves of folk medicinal plant benkara malabarica (lam) (Record no. 17347)
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| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20220826155327.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 220826b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | AIKTC-KRRC |
| Transcribing agency | AIKTC-KRRC |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 17632 |
| Author | Kalusalingam, Muthiah |
| 245 ## - TITLE STATEMENT | |
| Title | Estimation of antioxidant and cytotoxicity activities of extracts obtained from the leaves of folk medicinal plant benkara malabarica (lam) |
| 250 ## - EDITION STATEMENT | |
| Volume, Issue number | Vol.56(3), Jul-Sep |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Karnataka |
| Name of publisher, distributor, etc. | Association of Pharmaceutical Teachers of India (APTI) |
| Year | 2022 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Pagination | 838-845p. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Objectives:<br/>Benkara malabarica (Lam). is pharmacologically unexploited medicinal plant,<br/>used in the folklore Paliyar in India. Medicinal plant systems to treat many ailments such<br/>as cold, phlegm, stomach and body pains. The present investigation carried out with<br/>objective of finding an alternative antioxidant and cytotoxicity medicines from traditionally<br/>used medicinal plant and to provide ethnopharmacological information for its traditional<br/>usage. Materials and Methods: Petroleum ether, chloroform and methanol were used<br/>as solvents for the preparation of crude drug from the<br/>B. malabarica leaves. DPPH and<br/>O phenantroline reduction assay were used to estimate the antioxidant activities of the<br/>extracts, while MTT assay was used to determine the cytotoxicity of extracts using Hep<br/>G2 cell lines. Different concentration of extracts, in the range of 25, 50, 100, 150 and<br/>200 μg/ml was used for the determination of antioxidant activities. In case of cytotoxicity<br/>studies the extract concentration were 25, 50, 100, 200 and 500 μg/ml. Ascorbic acid<br/>was used as standard in antioxidant studies and doxorubicin was employed as standard<br/>in the cytotoxicity studies. Results: In both antioxidant and cytotoxicity studies, the<br/>activities were increased with the increase the concentrations of extracts. The potential<br/>of three extracts were in the following order, methanol, chloroform and petroleum ether<br/>in both antioxidant and cytotoxicity studies. Conclusion: The remarkable antioxidant and<br/>cytotoxicity activities, assayed through various<br/>in vitro models in the present study. This<br/>may be due to the presence of phytochemicals, such as phenol, flavonoid, alkaloid and<br/>glycosides in the extracts. Scientific data generated from the present study supports the<br/>usage of<br/>B. malabarica in the folklore medicinal system. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 4639 |
| Topical term or geographic name entry element | PHARMACEUTICS |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 17633 |
| Co-Author | Balakrishnan, Veluchamy |
| 773 0# - HOST ITEM ENTRY | |
| Title | Indian journal of pharmaceutical education and research |
| Place, publisher, and date of publication | Bengluru Association of Pharmaceutical Teachers of India (APTI) |
| International Standard Serial Number | 0019-5464 |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| URL | https://www.ijper.org/sites/default/files/IndJPhaEdRes-56-3-838.pdf |
| Link text | Click here |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Articles Abstract Database |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Home library | Current library | Shelving location | Date acquired | Total Checkouts | Barcode | Date last seen | Price effective from | Koha item type |
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| Dewey Decimal Classification | School of Pharmacy | School of Pharmacy | Archieval Section | 26/08/2022 | 2022-1397 | 26/08/2022 | 26/08/2022 | Articles Abstract Database |