Evaluation of the effect of methotrexate on psoriasis based on specialized pharmaceutical education (Record no. 17353)
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| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20220829102446.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 220829b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | AIKTC-KRRC |
| Transcribing agency | AIKTC-KRRC |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 17643 |
| Author | Wang, Lan |
| 245 ## - TITLE STATEMENT | |
| Title | Evaluation of the effect of methotrexate on psoriasis based on specialized pharmaceutical education |
| 250 ## - EDITION STATEMENT | |
| Volume, Issue number | Vol.56(2), Apr-June |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Karnataka |
| Name of publisher, distributor, etc. | Association of Pharmaceutical Teachers of India (APTI) |
| Year | 2022 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Pagination | 364-371p. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Background: Methotrexate (MTX) is still the gold standard therapy for moderate to<br/>severe psoriasis. There is a marked interpersonal variation in the therapeutic response<br/>and toxicity profile of MTX which brings difficulty for clinical application. Objectives: To<br/>establish the specialized pharmaceutical education (SPE) mode for psoriasis administrated<br/>with MTX and assess the therapeutic effect between cases received SPE and usual<br/>health care in the real-world. Materials and Methods: In this retrospective cohort study,<br/>patients of usual health care received prescription as proof of properly taking medicine<br/>and being required return to the hospital every 4 weeks. Patients of SPE intervention were<br/>referred to the pharmaceutical clinic every 4 weeks. Body surface area(BSA), psoriasis<br/>area severity index (PASI) of 0, 4, 8, 12 week, PASI 75 of 12 week and times of self-<br/>adjusting dosage were observational noted and analyzed. Results: Records of 12 cases<br/>of usual care and 16 cases of SPE received MTX for psoriasis were reviewed. The decline<br/>range of BSA of SPE was higher than that of usual care at 4 week, and the difference<br/>was statistically significant (<br/>p=0.043).The decline range of PASI of SPE was higher<br/>than that of usual care at 8 week and 12 week with statistically significant difference<br/>separately (<br/>p=0.048;<br/>p=0.029).Times of self-adjusting dosage was zero of SPE and was<br/>statistically significant different compared to that of usual care (<br/>p=0.026). Conclusion:<br/>Statistical significant faster improvement on efficacy with no significant difference of<br/>safety in the SPE than usual care came to the conclusion. The SPE conducted by the<br/>pharmacists appears suitable for the real world implementation. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 4639 |
| Topical term or geographic name entry element | PHARMACEUTICS |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 17644 |
| Co-Author | Shu, Dan |
| 773 0# - HOST ITEM ENTRY | |
| Place, publisher, and date of publication | Bengluru Association of Pharmaceutical Teachers of India (APTI) |
| International Standard Serial Number | 0019-5464 |
| Title | Indian journal of pharmaceutical education and research |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| URL | https://www.ijper.org/sites/default/files/IndJPhaEdRes-56-2-364_0.pdf |
| Link text | Click here |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Articles Abstract Database |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Home library | Current library | Shelving location | Date acquired | Total Checkouts | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | School of Pharmacy | School of Pharmacy | Archieval Section | 29/08/2022 | 2022-1420 | 29/08/2022 | 29/08/2022 | Articles Abstract Database |