Antimicrobial, antioxidant and cytotoxic activities of different fractions obtained from endophyticfusarium solani F01 isolated in catharanthus roseus collected in vietnam (Record no. 17364)
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| fixed length control field | a |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20220830093656.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 220830b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | AIKTC-KRRC |
| Transcribing agency | AIKTC-KRRC |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 17664 |
| Author | Nguyen, Tu |
| 245 ## - TITLE STATEMENT | |
| Title | Antimicrobial, antioxidant and cytotoxic activities of different fractions obtained from endophyticfusarium solani F01 isolated in catharanthus roseus collected in vietnam |
| 250 ## - EDITION STATEMENT | |
| Volume, Issue number | Vol.56(2), Apr-June |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Karnataka |
| Name of publisher, distributor, etc. | Association of Pharmaceutical Teachers of India (APTI) |
| Year | 2022 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Pagination | 461-469p. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Aim: Finding out the biological sources is essential for pharmaceutical field. Materials and<br/>Methods: Endophytic fungus was isolated from<br/>Catharanthus roseus originated in Vietnam<br/>and then identified by comparing, phylogeny analyzing its 18S sRNA sequence using<br/>Blast search and GenomeNet. The supernatant and sonicated mycelia were fractionated<br/>with methanol, ethyl acetate, hexane. All the fractions were used to test antimicrobial,<br/>antioxidant, cytotoxicity activities. Antimicrobial activities on<br/>Staphylococcus aureus<br/>ATCC 25923,<br/>Pseudomonas aeruginosa ATCC 27853,<br/>Serratia marcescens ATCC<br/>14756,<br/>Vibrio parahaemolyticus ATCC 17802, and<br/>Escherichia coli ATCC 25922 were<br/>performed by well diffusion method. In terms of antioxidant activities, reducing power<br/>and DPPH radical scavenging assay were done. The purification from methanol extract<br/>was performed. The purified compounds were used to test antioxidant activity. For<br/>cytotoxicity activity, sulforhodamine B assay was used to test the extracts and purified<br/>compounds on the breast cancer cell line (MCF-7). Results:<br/>Fusarium solani F01 was<br/>identified. The treated methanol extract from cell-free supernatant showed the highest<br/>activities and wider spectrum than ethyl acetate and hexane extracts. Mycelial extracts in<br/>these solvents did not show activities except ethyl acetate extract. The methanol crude<br/>extract from cell-free supernatant gave the higher reducing power (1.416 ± 0.067) than<br/>ascorbic acid (0.577 ± 0.01) while others were very low at the concentration (100 μg/<br/>ml). Only methanol extract obtained from supernatant showed moderate scavenging<br/>activity when comparison of their IC50 (9.17 g/ml) with IC50 of ascorbic acid (1.28 g/<br/>ml). Four compounds were obtained that showed antioxidant activities, but there was<br/>one purified compound showed low effects on MCF-7 while methanol extract gave the<br/>highest inhibition (80.34 ± 1.28). Conclusion: The study suggested fungus isolated<br/>from<br/>Catharanthus roseus could show and give many biological compounds that will be<br/>a potential source for pharmaceutical field. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 4639 |
| Topical term or geographic name entry element | PHARMACEUTICS |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 17665 |
| Co-Author | Doan, Vinh |
| 773 0# - HOST ITEM ENTRY | |
| Title | Indian journal of pharmaceutical education and research |
| Place, publisher, and date of publication | Bengluru Association of Pharmaceutical Teachers of India (APTI) |
| International Standard Serial Number | 0019-5464 |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| URL | https://www.ijper.org/sites/default/files/IndJPhaEdRes-56-2-461.pdf |
| Link text | Click here |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Articles Abstract Database |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Home library | Current library | Shelving location | Date acquired | Total Checkouts | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | School of Pharmacy | School of Pharmacy | Archieval Section | 30/08/2022 | 2022-1431 | 30/08/2022 | 30/08/2022 | Articles Abstract Database |