Protective effect of the aqueous extract of cyamopsis tetragonoloba seed against the paracetamol-induced toxicity in female wistar albino rats (Record no. 17378)
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| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20220901105443.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 220901b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | AIKTC-KRRC |
| Transcribing agency | AIKTC-KRRC |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 17687 |
| Author | Simon, Jerine Peter |
| 245 ## - TITLE STATEMENT | |
| Title | Protective effect of the aqueous extract of cyamopsis tetragonoloba seed against the paracetamol-induced toxicity in female wistar albino rats |
| 250 ## - EDITION STATEMENT | |
| Volume, Issue number | Vol.56(2), Apr-June |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Karnataka |
| Name of publisher, distributor, etc. | Association of Pharmaceutical Teachers of India (APTI) |
| Year | 2022 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Pagination | 580-588p. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Background: Paracetamol is also known as acetaminophen which is the most widely<br/>and commonly used painkiller drug among the overall human population. On excess<br/>usage and high dosage, paracetamol can cause liver injury, gastrointestinal damage<br/>and kidney damage.<br/>Cyamopsis tetragonoloba is the most commonly available<br/>plant in India which has weight loss properties as well as used to treat cancer and<br/>diabetes. Aim: This study is to estimate the potential effect of<br/>C. tetragonoloba against<br/>paracetamol-induced hepatotoxicity. Methodology: There were seven groups of rats<br/>which were divided as follows:Group-1 as Normal control, Group-2 administrated<br/>with paracetamol (900mg/kg b.w./day,<br/>i.p.), Group-3 is induced with paracetamol<br/>(900mg/kg b.w./day,<br/>i.p.) and<br/>C. tetragonoloba (500 mg/kg b.w./day,<br/>p.o.), Group-4<br/>is same as Group-3 however<br/>C. tetragonoloba dosage differs as 1000 mg/kg b.w./<br/>day,<br/>p.o.,Group-5 is given with paracetamol (900 mg/kg b.w./day,<br/>i.p.) and silymarin<br/>(25 mg/kg b.w./day,<br/>p.o.), Group-6and Group-7 is administrated with<br/>C. tetragonoloba<br/>(500 mg/kg b.w./day,<br/>p.o.) and<br/>C. tetragonoloba (1000 mg/kg b.w./day,<br/>p.o.)<br/>respectively. After 4 hrs of drug administration, the animals were sacrificed from which<br/>blood and organs were collected for the toxicity study. The samples were used for the<br/>analysis of liver and kidney enzyme markers, antioxidant assays and histopathological<br/>changes. Conclusion: The study has proven that<br/>C. tetragonoloba has a potential effect<br/>on the toxicity-induced groups. On compared to the standard drugs,<br/>C. tetragonoloba<br/>has shown better results. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 4639 |
| Topical term or geographic name entry element | PHARMACEUTICS |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 17688 |
| Co-Author | Namachivayam, Arunraj |
| 773 0# - HOST ITEM ENTRY | |
| Title | Indian journal of pharmaceutical education and research |
| Place, publisher, and date of publication | Bengluru Association of Pharmaceutical Teachers of India (APTI) |
| International Standard Serial Number | 0019-5464 |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| URL | https://www.ijper.org/sites/default/files/IndJPhaEdRes-56-2-580_1.pdf |
| Link text | Click here |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Articles Abstract Database |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Home library | Current library | Shelving location | Date acquired | Total Checkouts | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | School of Pharmacy | School of Pharmacy | Archieval Section | 01/09/2022 | 2022-1451 | 01/09/2022 | 01/09/2022 | Articles Abstract Database |