Formulation of mupirocin adsorbed silver nanoparticle with antibiofilm agents for enhancing antibacterial activit (Record no. 17595)
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| 000 -LEADER | |
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| fixed length control field | a |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20220922113657.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 220922b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | AIKTC-KRRC |
| Transcribing agency | AIKTC-KRRC |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 18027 |
| Author | Selliamman, Ravi Mahi Priya |
| 245 ## - TITLE STATEMENT | |
| Title | Formulation of mupirocin adsorbed silver nanoparticle with antibiofilm agents for enhancing antibacterial activit |
| 250 ## - EDITION STATEMENT | |
| Volume, Issue number | Vol.56(1), Jan-Mar |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Karnataka |
| Name of publisher, distributor, etc. | Association of Pharmaceutical Teachers of India (APTI) |
| Year | 2022 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Pagination | 50-57p. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Introduction: Biofilm is a complex structure of microbiome having different bacterial<br/>colonies or single type of cells in a group, adhere to the surface to produce infections.<br/>Nanoparticles (NPs) are widely used in different technological fields especially medicine<br/>because of their antibacterial properties. Silver nanoparticles (AgNPs) possess<br/>antimicrobial and antibiofilm property against various microbial infections. Objectives:<br/>The main objective of this study was to develop new formulations and characterization<br/>of mupirocin loaded silver nanoparticles with various anti biofilm agents. Methods: Silver<br/>nanoparticles formulations were prepared by tannic acid (TA) with trisodium citrate<br/>(TSC), Para-amino salicylic acid (PASA) and ascorbic acid (ASC) as both reducing and<br/>antibiofilm agents against<br/>Staphylococcus aureus followed by surface adsorption of<br/>Mupirocin (MUP). Transmission Electron Microscope (TEM) shows that the nanoparticles<br/>are roughly spherical in shape which was also confirmed by Atomic Force Microscopy<br/>(AFM). The particle size was in the range between 50 nm – 250 nm and found to be<br/>statistically significant (<br/>p<0.001) between the three AgNP formulations.<br/>In vitro drug<br/>release using the dialysis membrane showed a maximum release of 90% ± 2.343 in<br/>AgNPs (TSC TA) formulation at the end of 7 hr with the maximum drug entrapment<br/>of 93.75%. The formulations were tested for antimicrobial activity against<br/>S. aureus.<br/>The results were statistically compared using one way ANOVA and student t test.<br/>Conclusion: There is no significant difference in antibacterial activity between three<br/>AgNP formulations. However the best synergistic activity against planktonic<br/>S. aureus<br/>bacteria was shown by AgNP-PASA inspite of its minimal drug release when compared<br/>to AgNPs (TSC TA). |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 4639 |
| Topical term or geographic name entry element | PHARMACEUTICS |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 18028 |
| Co-Author | Roselin, Rajandurai Baby |
| 773 0# - HOST ITEM ENTRY | |
| International Standard Serial Number | 0019-5464 |
| Title | Indian journal of pharmaceutical education and research |
| Place, publisher, and date of publication | Bengluru Association of Pharmaceutical Teachers of India (APTI) |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| URL | https://www.ijper.org/sites/default/files/IndJPhaEdRes-56-1-50.pdf |
| Link text | Click here |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Articles Abstract Database |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Home library | Current library | Shelving location | Date acquired | Total Checkouts | Barcode | Date last seen | Price effective from | Koha item type |
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| Dewey Decimal Classification | School of Pharmacy | School of Pharmacy | Archieval Section | 22/09/2022 | 2022-1697 | 22/09/2022 | 22/09/2022 | Articles Abstract Database |