Effect of formulation variables on fabrication of risperidone loaded nanoparticles for sustained drug delivery (Record no. 17596)
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| 000 -LEADER | |
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| fixed length control field | a |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20220922114446.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 220922b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | AIKTC-KRRC |
| Transcribing agency | AIKTC-KRRC |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 18029 |
| Author | Gohil, Dipti |
| 245 ## - TITLE STATEMENT | |
| Title | Effect of formulation variables on fabrication of risperidone loaded nanoparticles for sustained drug delivery |
| 250 ## - EDITION STATEMENT | |
| Volume, Issue number | Vol.56(1), Jan-Mar |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Karnataka |
| Name of publisher, distributor, etc. | Association of Pharmaceutical Teachers of India (APTI) |
| Year | 2022 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Pagination | 58-64p. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Aim/ Background: Risperidone, an atypical antipsychotic agent, is used in the treatment of<br/>psychotic disorders due to its lower Extra Pyramidal side Effects (EPS) than conventional<br/>antipsychotics. Materials and Methods: The objective of the present investigation is<br/>to study the effect of formulation variables using 32 factorial design; on preparation of<br/>nanoparticles to provide sustained drug release for a prolonged period of time; enhancing<br/>therapeutic efficacy by reducing dose dependent side effects. Study include formulation<br/>of nanoparticles by the nanoprecipitation method and optimization of the formulation<br/>parameters such as Amount of Polymer and Surfactant concentration as independent<br/>variables and Particle size and % entrapment efficiency as dependent variables using<br/>design of experiment; a statistical tool. Results: Optimized formulation of nanoparticles<br/>was characterized for various physicochemical parameters. The particle size was found to<br/>be 213.3 nm with 82.89% drug entrapment. Conclusion:<br/>In vitro drug release study and<br/>Pharmacodynamic study portend promising results of drug delivery for longer duration.<br/>Key words: Schizophrenia, Risperidone, Nanoparticles, 32 factorial design, Catalepsy. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 4639 |
| Topical term or geographic name entry element | PHARMACEUTICS |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 18030 |
| Co-Author | Shah, Nirmal |
| 773 0# - HOST ITEM ENTRY | |
| Place, publisher, and date of publication | Bengluru Association of Pharmaceutical Teachers of India (APTI) |
| International Standard Serial Number | 0019-5464 |
| Title | Indian journal of pharmaceutical education and research |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| URL | https://www.ijper.org/sites/default/files/IndJPhaEdRes-56-1-58.pdf |
| Link text | Click here |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Articles Abstract Database |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Home library | Current library | Shelving location | Date acquired | Total Checkouts | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | School of Pharmacy | School of Pharmacy | Archieval Section | 22/09/2022 | 2022-1698 | 22/09/2022 | 22/09/2022 | Articles Abstract Database |