Smart spectrophotometric method development for simultaneous estimation of antidiabetic drugs in formulations (Record no. 17628)
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| 000 -LEADER | |
|---|---|
| fixed length control field | a |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20220923121750.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 220923b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | AIKTC-KRRC |
| Transcribing agency | AIKTC-KRRC |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 10005 |
| Author | Attimarad, Mahesh |
| 245 ## - TITLE STATEMENT | |
| Title | Smart spectrophotometric method development for simultaneous estimation of antidiabetic drugs in formulations |
| 250 ## - EDITION STATEMENT | |
| Volume, Issue number | Vol.56(1), Jan-Mar |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Karnataka |
| Name of publisher, distributor, etc. | Association of Pharmaceutical Teachers of India (APTI) |
| Year | 2022 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Pagination | 224-231p. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Background: An anti-diabetic formulation consisting of vildagliptin and remogliflozin was<br/>prescribed for better glycemic control. In the present study a simple, rapid derivative<br/>spectrophotometric methods were evolved to analyze these two analytes from the<br/>formulations. Methods: Two processed UV spectrophotometric methods were established<br/>by measuring the peak amplitude at zero-crossing of second derivative spectra of<br/>analytes. The second procedure comprehends the generation of zero - order spectra from<br/>the mixture of analyte spectra by division and multiplication by the pure analyte spectra<br/>to remove the effect of one of the analytes. Results: Both methods showed linearity<br/>concentrations in the range of 2-75 μg/ml for RGF and 2-50 μg/ml for VGT. The low<br/>LOD and LOQ found for RGF and VGT by both methods indicated the good sensitivity of<br/>the methods. The mean percentage recovery was 98.60 % and 100.78%, for RGF and<br/>98.81 % and 99.15 % for VGT, with low percent relative error. The % RSD for intra and<br/>inter-day precision was less than ±2%. Finally, the planned methods were employed<br/>for the assay of the VGT and RGF from the medicine and the outcomes were matched<br/>with the reported methods. Conclusion: The assay results of the formulation were in<br/>agreement with the concentration of labeled amount and no significant difference was<br/>observed in the results when compared to the reported method. Hence, the anticipated<br/>procedures could be applied for the routine quality control of formulations consisting of<br/>VGT and RGF. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 4639 |
| Topical term or geographic name entry element | PHARMACEUTICS |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 17684 |
| Co-Author | Venugopala, Katharigatta Narayanaswamy |
| 773 0# - HOST ITEM ENTRY | |
| International Standard Serial Number | 0019-5464 |
| Place, publisher, and date of publication | Bengluru Association of Pharmaceutical Teachers of India (APTI) |
| Title | Indian journal of pharmaceutical education and research |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| URL | https://www.ijper.org/sites/default/files/IndJPhaEdRes-56-1-224.pdf |
| Link text | Clikc here |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Articles Abstract Database |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Home library | Current library | Shelving location | Date acquired | Total Checkouts | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | School of Pharmacy | School of Pharmacy | Archieval Section | 23/09/2022 | 2022-1720 | 23/09/2022 | 23/09/2022 | Articles Abstract Database |