Chemometric assisted spectrophotometric method development for evaluation of torsemide and eplerenone in their combined tablet dosage forms (Record no. 17634)

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005 - DATE AND TIME OF LATEST TRANSACTION
control field 20220923151924.0
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fixed length control field 220923b xxu||||| |||| 00| 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency AIKTC-KRRC
Transcribing agency AIKTC-KRRC
100 ## - MAIN ENTRY--PERSONAL NAME
9 (RLIN) 18084
Author Madhuri A.
245 ## - TITLE STATEMENT
Title Chemometric assisted spectrophotometric method development for evaluation of torsemide and eplerenone in their combined tablet dosage forms
250 ## - EDITION STATEMENT
Volume, Issue number Vol.56(1), Jan-Mar
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Karnataka
Name of publisher, distributor, etc. Association of Pharmaceutical Teachers of India (APTI)
Year 2022
300 ## - PHYSICAL DESCRIPTION
Pagination 253-263p.
520 ## - SUMMARY, ETC.
Summary, etc. Aim: In a present work two drugs Torsemide and Eplerenone were estimated from their<br/>combined tablet dosage forms by applying chemometric assisted spectrophotometric<br/>method. Methods: The methods are based on chemometrics a (multivariate) method<br/>which includes classical least square (CLS) and inverse least square (ILS). These methods<br/>were employed for simultaneous determination of Torsemide and Eplerenone in tablet<br/>dosage forms without any prior separation of components. For these methods the<br/>overlapping spectra of two drugs not subjected any conversions. The data processing of<br/>chemometric was accomplished by using software named Chemometrics Toolbox 3.02<br/>which is associated with MATLAB 6 and excel. Results: The results obtained from CLS<br/>and ILS methods were compared statistically. These chemometric methods were applied<br/>for the determination of these two drugs in their marketed tablet dosage form without<br/>any prior separation procedure of the drugs. The mean percent recoveries and values<br/>of relative standard deviation for these two methods were found to be 99.72/0.536<br/>for Torsemide and 100.06/0.384 for Eplerenone. Conclusion: The two chemometric<br/>methods developed can be successfully applied for the quantitative estimation of drugs<br/>from their dosage form.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
9 (RLIN) 4639
Topical term or geographic name entry element PHARMACEUTICS
700 ## - ADDED ENTRY--PERSONAL NAME
9 (RLIN) 18086
Co-Author Patel, Dipti
773 0# - HOST ITEM ENTRY
Place, publisher, and date of publication Bengluru Association of Pharmaceutical Teachers of India (APTI)
Title Indian journal of pharmaceutical education and research
International Standard Serial Number 0019-5464
856 ## - ELECTRONIC LOCATION AND ACCESS
URL https://www.ijper.org/sites/default/files/IndJPhaEdRes-56-1-255.pdf
Link text Click here
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    Dewey Decimal Classification     School of Pharmacy School of Pharmacy Archieval Section 23/09/2022   2022-1724 23/09/2022 23/09/2022 Articles Abstract Database
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