Establishment of a rapid and highly sensitive reverse-phase high-performance liquid chromatography based analytical assay method for duvelisib (Record no. 17643)
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| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20220923155207.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 220923b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | AIKTC-KRRC |
| Transcribing agency | AIKTC-KRRC |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 18093 |
| Author | Sonawane, Dipali |
| 245 ## - TITLE STATEMENT | |
| Title | Establishment of a rapid and highly sensitive reverse-phase high-performance liquid chromatography based analytical assay method for duvelisib |
| 250 ## - EDITION STATEMENT | |
| Volume, Issue number | Vol.56(1), Jan-Mar |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Karnataka |
| Name of publisher, distributor, etc. | Association of Pharmaceutical Teachers of India (APTI) |
| Year | 2022 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Pagination | 287-295p. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Background: Duvelisib is an antineoplastic agent that received global approval from the<br/>United States Food and Drug Administration in 2018. An extensive literature search<br/>revealed that analytical method for the quantification of duvelisib at nanogram level is not<br/>available till date. A highly sensitive analytical method is necessary to analyze diversified<br/>samples containing trace levels of the analyte such as dissolution samples of sustained<br/>release formulation, cross-contamination study samples etc. Materials and Methods:<br/>Primary aim of this research was to develop a high throughput, accurate, reproducible,<br/>and highly sensitive high performance liquid chromatography method for quantification<br/>of duvelisib and validate according to the International Council for Harmonisation of<br/>Technical Requirements for Pharmaceuticals for Human Use and Association of Official<br/>Analytical Collaboration guidelines. Results: A linear relationship was confirmed over<br/>70 to 5000 ng/mL concentrations with a limit of detection value of 20 ng/mL. The<br/>intra and inter-day precision were found to be 0.97 to 1.87% and 1.25 to 1.99%,<br/>respectively. Conclusion: This is the first time to report a quantitative assay method<br/>for duvelisib, which can quantify the analyte even at the nanogram level. This method<br/>will be suitable for sample analysis of quality control, stability, cross-contamination,<br/>dissolution study of sustained-release formulation and effluent analysis of duvelisib in<br/>pharmaceutical industries and research laboratories. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 4639 |
| Topical term or geographic name entry element | PHARMACEUTICS |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 18094 |
| Co-Author | Sahu, Amit Kumar |
| 773 0# - HOST ITEM ENTRY | |
| Title | Indian journal of pharmaceutical education and research |
| Place, publisher, and date of publication | Bengluru Association of Pharmaceutical Teachers of India (APTI) |
| International Standard Serial Number | 0019-5464 |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| URL | https://www.ijper.org/sites/default/files/IndJPhaEdRes-56-1-287.pdf |
| Link text | Click here |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Articles Abstract Database |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Home library | Current library | Shelving location | Date acquired | Total Checkouts | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | School of Pharmacy | School of Pharmacy | Archieval Section | 23/09/2022 | 2022-1728 | 23/09/2022 | 23/09/2022 | Articles Abstract Database |