Studies on biochemical, oxidative and genotoxicity alterations following vas blockage with reversible inhibition of sperm under guidance and reversal in rats (Record no. 18266)
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| fixed length control field | a |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20221118101118.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 221118b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | AIKTC-KRRC |
| Transcribing agency | AIKTC-KRRC |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 19128 |
| Author | Ansari, Abdul S. |
| 245 ## - TITLE STATEMENT | |
| Title | Studies on biochemical, oxidative and genotoxicity alterations following vas blockage with reversible inhibition of sperm under guidance and reversal in rats |
| 250 ## - EDITION STATEMENT | |
| Volume, Issue number | Vol.54(1), Jan-Feb |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Mumbai |
| Name of publisher, distributor, etc. | Wolter Kluwer |
| Year | 2022 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Pagination | 33-40p. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | CONTEXT: Vas obstruction with reversible inhibition of sperm under guidance (RISUG) for<br/>contraception and its reversal, may cause oxidative stress or inimical effects on male reproductive<br/>functions.<br/>OBJECTIVE: To evaluate the biochemical and genotoxicity at the level of reactive oxygen<br/>species (ROS) following vas occlusion with RISUG and its reversal by Dimethyl sulphoxide (DMSO)<br/>and 5% NaHCO3 in Wistar albino rats.<br/>SETTINGS AND DESIGN: Animals were divided into seven groups (n = 10), namely sham‑operated<br/>control, short‑term vas occlusion with RISUG for 90 days, reversal with DMSO and 5% NaHCO3,<br/>long‑term vas occlusion with RISUG for 360 days, reversal with DMSO and 5% NaHCO3.<br/>MATERIALS AND METHODS: Biochemical markers in reproductive tissues, hematology, serum<br/>biochemistry, serum electrolytes and ROS measuring indicators, e.g., lipid peroxidation, superoxide<br/>dismutase, catalase, glutathione peroxidase, and glutathione S‑transferase were examined.<br/>STATISTICAL ANALYSIS USED: One‑way analysis of variance test was performed for analyses of<br/>data obtained in this study using the SPSS 10.0 software (SPSS Inc., Chicago, IL, USA).<br/>RESULTS: The tissue and clinical chemistry did not show appreciable alterations in RISUG injected<br/>and reversal Groups (II‑VII) as compared to sham control. The genotoxicity and various ROS markers<br/>fluctuated within control limits following short‑ and long‑term vas occlusion and reversal.<br/>CONCLUSIONS: The study suggested that the reversal procedures, following RISUG contraception,<br/>were not associated with any kind of toxicological manifestations. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 4774 |
| Topical term or geographic name entry element | PHARMACOLOGY |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 19129 |
| Co-Author | Mubarik Hussain |
| 773 0# - HOST ITEM ENTRY | |
| International Standard Serial Number | 0253-7613 |
| Place, publisher, and date of publication | Andheri - Mumbai Wolters Kluwer India Private Limited |
| Title | Indian Journal of Pharmacology |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| URL | https://www.ijp-online.com/temp/IndianJPharmacol54133-1604208_042722.pdf |
| Link text | Click here |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Articles Abstract Database |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Home library | Current library | Shelving location | Date acquired | Total Checkouts | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | School of Pharmacy | School of Pharmacy | Archieval Section | 18/11/2022 | 2022-2149 | 18/11/2022 | 18/11/2022 | Articles Abstract Database |