Antioxidant potential and chemical composition of ophiorrhiza jacobii: a promising medicinal plant endemic to western ghats (Record no. 18322)
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| 000 -LEADER | |
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| fixed length control field | a |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20221122113252.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 221122b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | AIKTC-KRRC |
| Transcribing agency | AIKTC-KRRC |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 19212 |
| Author | Preethamol, S. N. |
| 245 ## - TITLE STATEMENT | |
| Title | Antioxidant potential and chemical composition of ophiorrhiza jacobii: a promising medicinal plant endemic to western ghats |
| 250 ## - EDITION STATEMENT | |
| Volume, Issue number | Vol.84(2), Mar-Apr |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Mumbai |
| Name of publisher, distributor, etc. | Indian Journal of Pharmaceutical Science |
| Year | 2022 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Pagination | 407-414p. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Ophiorrhiza jacobii, is a therapeutically less explored species, belonging to the family Rubiaceae and endemic<br/>to the Western Ghats. The present study was aimed to evaluate the antioxidant potential and chemical<br/>composition of the methanolic extract of the plant Ophiorrhiza jacobii using various in vitro methods and<br/>gas chromatography-mass spectrometric analysis respectively. Phytochemical screening of the extract<br/>revealed the presence of numerous bioactive secondary metabolites like phenols, terpenoids, sterols and<br/>tannins that might contribute to the medicinal properties of the plant. The maximum percentage inhibition<br/>obtained in 2,2-diphenyl-1-picrylhydrazyl, hydroxyl, nitric oxide and superoxide radical scavenging assays<br/>were 72.01 %±0.79 %, 70.24 %±0.90 %, 67.37 %±1.20 % and 76.00 %±1.07 % respectively. In all the<br/>assays, a dose-dependent increase in free radical scavenging activity was exhibited by the plant extract and<br/>the percentage inhibition of the radicals showed that the plant possesses significant antioxidant capacity.<br/>Gas chromatography-mass spectrometry analysis revealed several antioxidant compounds like phytol,<br/>vitamin E, stigmasterol, solanesol and n-hexadecanoic acid suggesting that the plant can be a potential<br/>source of natural antioxidant to treat various ailments related to oxidative stress. Till date, no literature<br/>is available on the evaluation of the medicinal properties of Ophiorrhiza jacobii and this study forms the<br/>first report on the antioxidant potential and chemical composition of the plant. The presence of terpenoids,<br/>phytosterols, terpene alcohols, fatty acids and their esters, also suggests that the plant can be a novel source<br/>for the development of new therapeutic agents to treat various health disorders. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 4639 |
| Topical term or geographic name entry element | PHARMACEUTICS |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 19213 |
| Co-Author | Thoppil, J. E. |
| 773 0# - HOST ITEM ENTRY | |
| Title | Indian journal of pharmaceutical sciences |
| Place, publisher, and date of publication | New Delhi |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| URL | https://www.ijpsonline.com/articles/antioxidant-potential-and-chemical-composition-of-emophiorrhiza-jacobiiem-a-promising-medicinal-plant-endemic-to-western.pdf |
| Link text | Click here |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Articles Abstract Database |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Home library | Current library | Shelving location | Date acquired | Total Checkouts | Barcode | Date last seen | Price effective from | Koha item type |
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| Dewey Decimal Classification | School of Pharmacy | School of Pharmacy | Archieval Section | 22/11/2022 | 2022-2182 | 22/11/2022 | 22/11/2022 | Articles Abstract Database |