Case presentation on ofloxacin induced dermal hypersensitivity reaction (Record no. 18834)
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| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20230207105813.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 230207b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | AIKTC-KRRC |
| Transcribing agency | AIKTC-KRRC |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 19945 |
| Author | Bhavanam, Divya |
| 245 ## - TITLE STATEMENT | |
| Title | Case presentation on ofloxacin induced dermal hypersensitivity reaction |
| 250 ## - EDITION STATEMENT | |
| Volume, Issue number | Vol.14(3) |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | M P |
| Name of publisher, distributor, etc. | Innovare Academic Sciences Pvt Ltd |
| Year | 2022 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Pagination | 53-56p. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Ofloxacin is a second-generation fluoroquinolone and is highly effective against a wide range of bacterial infections. Fluoroquinolones are well-tolerated drugs with mild-to-moderate adverse effects such as gastrointestinal disturbances, skin reactions, and neurological reactions. These are widely used antimicrobials, which can cause cutaneous ADRs in about 1%–2% of patients. Hypersensitivity reactions due to ofloxacin are found rarely, ranging in frequency from 0.4% to 2%, respectively. This case report highlights one such event of cutaneous ADR by the use of ofloxacin injection causing Injection site reaction after a few minutes of Ofloxacin infusion. Based on history and clinical examination patient was diagnosed as ofloxacin induced hypersensitivity reaction and was successfully treated with antihistamines and corticosteroids. General management of ADR includes withdrawal/suspension, dose reduction of the suspected drug, and administration of supportive therapy. In this case, the suspected drugs were withdrawn and the patient was treated symptomatically. Pharmacovigilance should be a part of patient care to reduce the occurrence of adverse drug reactions and also encourage practitioners in reporting to gather more and more data regarding adverse drug reactions. Due to the rarity of Ofloxacin induced ADRs this article sheds light on one of such cases to help in pharmacovigilance. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 4639 |
| Topical term or geographic name entry element | PHARMACEUTICS |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 19946 |
| Co-Author | Thankachan, Ledo |
| 773 0# - HOST ITEM ENTRY | |
| Place, publisher, and date of publication | Bhopal Innovare Academic Sciences Pvt Ltd |
| Title | International journal of pharmacy and pharmaceutical science |
| International Standard Serial Number | 2656-0097 |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| URL | https://innovareacademics.in/journals/index.php/ijpps/article/view/43640/26101 |
| Link text | Click here |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Articles Abstract Database |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Home library | Current library | Shelving location | Date acquired | Total Checkouts | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | School of Pharmacy | School of Pharmacy | Archieval Section | 07/02/2023 | 2023-0292 | 07/02/2023 | 07/02/2023 | Articles Abstract Database |