Cost-minimization analysis of escitalopram, fluoxetine, and amitriptyline in the treatment of depression (Record no. 20609)

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003 - CONTROL NUMBER IDENTIFIER
control field OSt
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20240118095358.0
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fixed length control field 240118b xxu||||| |||| 00| 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency AIKTC-KRRC
Transcribing agency AIKTC-KRRC
100 ## - MAIN ENTRY--PERSONAL NAME
9 (RLIN) 22803
Author Salian, Harshit Hemant
245 ## - TITLE STATEMENT
Title Cost-minimization analysis of escitalopram, fluoxetine, and amitriptyline in the treatment of depression
250 ## - EDITION STATEMENT
Volume, Issue number Vol.55(5), Sep-Oct
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Mumbai
Name of publisher, distributor, etc. Wolter Kluwer
Year 2023
300 ## - PHYSICAL DESCRIPTION
Pagination 293-298p.
520 ## - SUMMARY, ETC.
Summary, etc. INTRODUCTION:<br/><br/>Escitalopram, fluoxetine, and amitriptyline are the drugs commonly used in the treatment of depression. The pharmacoeconomic evaluation of these drugs becomes relevant as they are prescribed for a long period of time, and depression causes a significant economic burden. The cost-minimization study would contribute to bringing down the annual treatment costs, leading to better medication adherence and ultimately better patient outcomes.<br/>MATERIALS AND METHODS:<br/><br/>All drug prices are mentioned in Indian National Rupee (INR). All expenses are based on 2022 pricing. No cost discounting was used because all expenditures were calculated over a year. We considered hypothetical scenarios where the patient was prescribed the lowest possible dose for depression, an equivalent antidepressant dose, a defined daily dose, and the maximum acceptable therapeutic dose for depression.<br/>RESULTS:<br/><br/>Annual average treatment costs of amitriptyline, escitalopram, and fluoxetine in patients with depression at baseline with equivalent dosing as mono-drug therapy were 2765.53, 2914.78, and 1422.72 rupees (INR), respectively. Savings were high when the patient was shifted to fluoxetine from either escitalopram or amitriptyline. The savings from switching to fluoxetine were 50.66% and 56.42% from escitalopram and amitriptyline, respectively.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
9 (RLIN) 4774
Topical term or geographic name entry element PHARMACOLOGY
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9 (RLIN) 22804
Co-Author Raghav, M. V.
773 0# - HOST ITEM ENTRY
Place, publisher, and date of publication Andheri - Mumbai Wolters Kluwer India Private Limited
International Standard Serial Number 0253-7613
Title Indian Journal of Pharmacology
856 ## - ELECTRONIC LOCATION AND ACCESS
URL https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10751525/?report=classic
Link text Click here
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    Dewey Decimal Classification     School of Pharmacy School of Pharmacy Archieval Section 18/01/2024   2024-0078 18/01/2024 18/01/2024 Articles Abstract Database
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