Genetic polymorphisms associated with sepsis incidence, severity, and outcomes among neonates: A mini‑review (Record no. 20617)
[ view plain ]
| 000 -LEADER | |
|---|---|
| fixed length control field | a |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20240118153513.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 240118b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | AIKTC-KRRC |
| Transcribing agency | AIKTC-KRRC |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 22819 |
| Author | Darnifayanti, Darnifayanti |
| 245 ## - TITLE STATEMENT | |
| Title | Genetic polymorphisms associated with sepsis incidence, severity, and outcomes among neonates: A mini‑review |
| 250 ## - EDITION STATEMENT | |
| Volume, Issue number | Vol.14(4), Oct-Dec |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Mumbai |
| Name of publisher, distributor, etc. | Wolter Kluwer |
| Year | 2023 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Pagination | 289-293p. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Genetic variation remains a topic of great interest due to its potential as a risk factor<br/>for various diseases. Interactions between genes contribute to diverse phenotypes in<br/>response to factors such as infection. The impact of genetic background on susceptibility<br/>and clinical outcomes, particularly in neonatal sepsis, has gained recognition. The<br/>variability in sepsis susceptibility and outcomes can be attributed to the genetic diversity<br/>in coding regions and regulatory elements of genes related to innate immune response.<br/>Recent advances in genomics and technology have shed light on genetic polymorphisms<br/>among humans, often represented by single‑nucleotide polymorphisms (SNPs).<br/>These SNPs encode proteins crucial for recognizing and responding to pathogenic<br/>bacteria, including Toll‑like receptor 4, CD14, tumor necrosis factor‑alpha, as well<br/>as interleukin‑1‑10. This literature review specifically discusses the involvement of<br/>genetic polymorphism during the pathogenesis stage of sepsis, with an emphasis on<br/>previous research findings in neonatal sepsis cases, aiming to discuss the implications<br/>of polymorphism in sepsis susceptibility and outcomes. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 4639 |
| Topical term or geographic name entry element | PHARMACEUTICS |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 22820 |
| Co-Author | Akmal, Muslim |
| 773 0# - HOST ITEM ENTRY | |
| International Standard Serial Number | 2231-4040 |
| Title | Journal of advanced pharmaceutical technology and research |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| URL | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10723165/pdf/JAPTR-14-289.pdf |
| Link text | Click here |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Articles Abstract Database |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Home library | Current library | Shelving location | Date acquired | Total Checkouts | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | School of Pharmacy | School of Pharmacy | Archieval Section | 18/01/2024 | 2024-0086 | 18/01/2024 | 18/01/2024 | Articles Abstract Database |