Genital ulcers following all-trans-retinoic acid therapy A case series with review of literature (Record no. 20836)

MARC details
000 -LEADER
fixed length control field a
003 - CONTROL NUMBER IDENTIFIER
control field OSt
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20240403115620.0
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fixed length control field 240403b xxu||||| |||| 00| 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency AIKTC-KRRC
Transcribing agency AIKTC-KRRC
100 ## - MAIN ENTRY--PERSONAL NAME
9 (RLIN) 8218
Author Saraswat, Neerja
245 ## - TITLE STATEMENT
Title Genital ulcers following all-trans-retinoic acid therapy A case series with review of literature
250 ## - EDITION STATEMENT
Volume, Issue number Vol.55(2), Mar-Apr
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Mumbai
Name of publisher, distributor, etc. Wolter Kluwer
Year 2023
300 ## - PHYSICAL DESCRIPTION
Pagination 138-140p.
520 ## - SUMMARY, ETC.
Summary, etc. All-trans-retinoic acid (ATRA) has transformed the treatment of acute promyelocytic leukemia. Most of the adverse effects associated with this drug are minor barring differentiation syndromes. Genital ulcers feature among the underreported adverse effects of ATRA which needs to be kept in mind to avoid life-threatening complications. We describe two cases who developed genital ulcers while treated with ATRA.<br/>All-trans-retinoic acid (ATRA) has become a landmark drug in the management of acute promyelocytic leukemia (APML). Its combination with other systemic therapy leads to the induction of complete remission in 90% cases of APML. Although differentiation syndrome (DS) is the most dreaded and life-threatening adverse effects of ATRA, a variety of other side effects such as xerosis, xerostomia, and cheilitis are also reported. Genital ulceration is one of the rare adverse effects of ATRA. Herein, we report two cases, one male and a female between the age of 36–40 years who presented to us with ATRA-induced genital ulceration.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
9 (RLIN) 4774
Topical term or geographic name entry element PHARMACOLOGY
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9 (RLIN) 33
Co-Author Sushil, Kumar
773 0# - HOST ITEM ENTRY
Place, publisher, and date of publication Andheri - Mumbai Wolters Kluwer India Private Limited
International Standard Serial Number 0253-7613
Title Indian Journal of Pharmacology
856 ## - ELECTRONIC LOCATION AND ACCESS
URL https://journals.lww.com/iphr/fulltext/2023/55020/genital_ulcers_following_all_trans_retinoic_acid.9.aspx
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942 ## - ADDED ENTRY ELEMENTS (KOHA)
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    Dewey Decimal Classification     School of Pharmacy School of Pharmacy Archieval Section 03/04/2024   2024-0394 03/04/2024 03/04/2024 Articles Abstract Database
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