Chemo metric assisted method development for the estimation of paracetamol, etoricoxib and thiocolchicoside in combined formulation (Record no. 22102)
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| 000 -LEADER | |
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| fixed length control field | a |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250109160235.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 250109b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | AIKTC-KRRC |
| Transcribing agency | AIKTC-KRRC |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 25053 |
| Author | Uparwad, Shital D. |
| 245 ## - TITLE STATEMENT | |
| Title | Chemo metric assisted method development for the estimation of paracetamol, etoricoxib and thiocolchicoside in combined formulation |
| 250 ## - EDITION STATEMENT | |
| Volume, Issue number | Vol.14(3), Jul-Sep |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Raipur |
| Name of publisher, distributor, etc. | Asian Pharma Press |
| Year | 2024 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Pagination | 135-141p. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Chemometric based analytical method was developed for the estimation of Paracetamol (PCM), Etoricoxib (ECB) and Thiocolchicoside (TCS) by UV-VIS spectrophotometry. Spectroscopic technique, a simple, rapid, precise and accurate process for amount estimation is still in great use for analyst. For estimation of these drugs, solvent alcohol 90% was utilised and 248.5nm, 287nm and 380.5nm were the wavelength of absorbance measurement for PCM, ECB and TCS respectively. Effect of input variables on spectrum characteristics were studied for selection of critical parameters and developed method was validated as per ICH Q 2 R1 regulatory guidelines. Linearity of all these three drugs was ascertained over the conc range 1-14µg/ml for PCM and 1-24 µg/ml for both ECB and TCS. The accuracy of assay was found 102.66% for PCM, 98.56% for ECB and 98.02 % for TCS; and the precision study was shown acceptable data as %RSD data varied from 0.5382 to 1.6227 for PCM, from 0.4280 to 1.0521 for ECB and from 0.1438 to 0.8553 for TCS. The developed method is rigid, robust and efficient for the estimation of PCM, ECB and TCS from the combined composition of dosage form. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 4639 |
| Topical term or geographic name entry element | PHARMACEUTICS |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 25054 |
| Co-Author | Khapne, Sonali M. |
| 773 0# - HOST ITEM ENTRY | |
| International Standard Serial Number | 2231-5667 |
| Title | Asian journal of pharmaceutical analysis |
| Place, publisher, and date of publication | Raipur A & V Publications |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| URL | https://ajpaonline.com/AbstractView.aspx?PID=2024-14-3-5 |
| Link text | Click here |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Articles Abstract Database |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Home library | Current library | Shelving location | Date acquired | Total Checkouts | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | School of Pharmacy | School of Pharmacy | Archieval Section | 09/01/2025 | 2025-0018 | 09/01/2025 | 09/01/2025 | Articles Abstract Database |