Enhancement of nootropic effect of duloxetine and bupropion by caffeine in mice (Record no. 23736)

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fixed length control field 01853 a2200217 4500
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control field OSt
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20251205095835.0
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fixed length control field 251205b |||||||| |||| 00| 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency AIKTC-KRRC
Transcribing agency AIKTC-KRRC
100 ## - MAIN ENTRY--PERSONAL NAME
Author Kale, Pravin Popatrao
9 (RLIN) 16741
245 ## - TITLE STATEMENT
Title Enhancement of nootropic effect of duloxetine and bupropion by caffeine in mice
250 ## - EDITION STATEMENT
Volume, Issue number Vol.47(2), Mar-Apr
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Mumbai
Name of publisher, distributor, etc. Wolter Kluwer
Year 2015
300 ## - PHYSICAL DESCRIPTION
Pagination 199-201p.
520 ## - SUMMARY, ETC.
Summary, etc. The existing evidence suggests an association between depression and memory impairment. The objective of present study was to assess the effect of low dose caffeine with duloxetine and bupropion on memory.<br/>Materials and Methods: <br/><br/>Mice were divided randomly into seven groups. Intra-peritoneal treatment of normal saline (10 ml/kg), caffeine (10 mg/kg), duloxetine (10 mg/kg), bupropion alone (10 mg/kg), caffeine + duloxetine (5 mg/kg, each), caffeine + bupropion (5 mg/kg, each), and bupropion + duloxetine (5 mg/kg, each) were given to groups I-VII, respectively. Elevated plus maze was used to evaluate transfer latency (TL) and Morris water maze was used to estimate the time spent in target quadrant.<br/>Results: <br/><br/>Caffeine with duloxetine treated group was better than other combination treated groups in terms of a significant decrease in TL and increase in the time spent in target quadrant recorded.<br/>Conclusion: <br/><br/>Combining lower dose of caffeine with duloxetine may enhance cognitive benefits than respective monotherapies.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element PHARMACOLOGY
9 (RLIN) 4774
700 ## - ADDED ENTRY--PERSONAL NAME
Co-Author Addepalli, Veeranjaneyulu
9 (RLIN) 27690
773 0# - HOST ITEM ENTRY
Title Indian Journal of Pharmacology
International Standard Serial Number 0253-7613
Place, publisher, and date of publication Andheri - Mumbai Wolters Kluwer India Private Limited
856 ## - ELECTRONIC LOCATION AND ACCESS
URL https://journals.lww.com/iphr/fulltext/2015/47020/enhancement_of_nootropic_effect_of_duloxetine_and.14.aspx
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    Dewey Decimal Classification     School of Pharmacy School of Pharmacy Archieval Section 05/12/2025   2025-1773 05/12/2025 05/12/2025 Articles Abstract Database
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