Antimicrobial drug prescribing patterns for community-acquired pneumonia in hospitalized patients A retrospective pilot study from New Delhi, India (Record no. 23779)

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040 ## - CATALOGING SOURCE
Original cataloging agency AIKTC-KRRC
Transcribing agency AIKTC-KRRC
100 ## - MAIN ENTRY--PERSONAL NAME
Author Kotwani, Anita
9 (RLIN) 27749
245 ## - TITLE STATEMENT
Title Antimicrobial drug prescribing patterns for community-acquired pneumonia in hospitalized patients A retrospective pilot study from New Delhi, India
250 ## - EDITION STATEMENT
Volume, Issue number Vol.47(4), Jul-Aug
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Mumbai
Name of publisher, distributor, etc. Wolter Kluwer
Year 2015
300 ## - PHYSICAL DESCRIPTION
Pagination 375-382p.
520 ## - SUMMARY, ETC.
Summary, etc. The objective of this study was to determine patterns and frequency of antimicrobial drug use among hospitalized patients with community-acquired pneumonia (CAP).<br/>Methodology: <br/><br/>A retrospective 5 years (April 2007–March 2012) detailed medical record review of patients diagnosed with CAP and discharged to home from Non-Intensive Care Unit respiratory medicine wards of two public hospitals in Delhi.<br/>Results: <br/><br/>A total of 261 medical records were analyzed. Over the 5 years, 82.0% (2007–08), 78.6% (2008–09), 59.5% (2009–10), 64.7% (2010–11), and 67.8% (2011–12) patients were prescribed two antimicrobials. In the last two study years, the proportion of patients receiving three antimicrobials increased (from 2.0% to 26.5% and 28.8%), while the proportion receiving monotherapy decreased (from 16.0% to 8.8% and 3.4%). In accordance with guidelines, beta-lactams and macrolides were the two most frequently prescribed antimicrobials (34.1%). However, newer generation beta-lactams were prescribed. A total of 37 patients were prescribed beta-lactam-tazobactam combination preparations. Overall, beta-lactams constituted more than 40% of prescriptions while macrolides were the second most prescribed class. Cephalosporin prescriptions significantly increased (P < 0.01) and penicillin prescriptions significantly decreased over study periods. The prescription of fluoroquinolones also decreased (21.5–6.0%, P < 0.01) and aminoglycoside prescription ranged from 9.7% to 16.4%, over 5 years. Reasons for prescribing three antimicrobials, use of aminoglycosides, or higher-end/reserve antibiotics were not mentioned in the medical records. There were no hospital-specific guidelines for doctors to follow in the treatment of CAP.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element PHARMACOLOGY
9 (RLIN) 4774
700 ## - ADDED ENTRY--PERSONAL NAME
Co-Author Santosh Kumar
9 (RLIN) 10967
773 0# - HOST ITEM ENTRY
International Standard Serial Number 0253-7613
Place, publisher, and date of publication Andheri - Mumbai Wolters Kluwer India Private Limited
Title Indian Journal of Pharmacology
856 ## - ELECTRONIC LOCATION AND ACCESS
URL https://journals.lww.com/iphr/fulltext/2015/47040/antimicrobial_drug_prescribing_patterns_for.7.aspx
Link text Click here
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