Efficacy of Spirulina platensis in improvement of the reproductive performance and easing teratogenicity in hyperglycemic albino mice (Record no. 23789)

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control field 20251212121040.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 251212b |||||||| |||| 00| 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency AIKTC-KRRC
Transcribing agency AIKTC-KRRC
100 ## - MAIN ENTRY--PERSONAL NAME
Author Punj, Pankaj Pranay
9 (RLIN) 27764
245 ## - TITLE STATEMENT
Title Efficacy of Spirulina platensis in improvement of the reproductive performance and easing teratogenicity in hyperglycemic albino mice
250 ## - EDITION STATEMENT
Volume, Issue number Vol.47(4), Jul-Aug
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Mumbai
Name of publisher, distributor, etc. Wolter Kluwer
Year 2015
300 ## - PHYSICAL DESCRIPTION
Pagination 430-435p.
520 ## - SUMMARY, ETC.
Summary, etc. The present study evaluates the therapeutic efficacy of cell suspension of Spirulina platensis (SP) on estrous cycle, fetal development and embryopathy in alloxan (AXN) induced hyperglycemic mice.<br/>Materials and Methods: <br/><br/>Diabetes was induced by intra-peritoneal administration of AXN. Mice with blood glucose level above 200 mg/dl were divided into Group I (control), Group II (diabetic control), Group III (diabetic control mice fed with SP), and Group IV (control mice fed with SP). Litter counts, estrous cycles, percent survival of litter, and gestation length were recorded.<br/>Results: <br/><br/>In hyperglycemic mice, a significant (P < 0.05) increase in duration of diestrus (14.48%), estrus (84.21%), and metestrus (164.15%) with concomitant decrease in proestrus phase by 26.13% was recorded when compared with control. Reduction in litter count and survival of litter was 68.67% and 88.38%, respectively, whereas gestation length increased to 14.51% day in diabetic mice, but recovery in these parameters was observed (P < 0.05) when subjected to SP treatment. SP resulted in increased fertility rate from 77.5% to 82.5% and dropped off resorption of the fetus to 33.73% while the survival rate of offspring of diabetic mice went up to 88.89% from 83.61%.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element PHARMACOLOGY
9 (RLIN) 4774
773 0# - HOST ITEM ENTRY
International Standard Serial Number 0253-7613
Title Indian Journal of Pharmacology
Place, publisher, and date of publication Andheri - Mumbai Wolters Kluwer India Private Limited
856 ## - ELECTRONIC LOCATION AND ACCESS
URL https://journals.lww.com/iphr/fulltext/2015/47040/efficacy_of_spirulina_platensis_in_improvement_of.17.aspx
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    Dewey Decimal Classification     School of Pharmacy School of Pharmacy Archieval Section 12/12/2025   2025-1819 12/12/2025 12/12/2025 Articles Abstract Database
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