Synthesis, characterization and antimalarial-antimicrobial studies of some novel derivatives of chloroquinoline base pyrazoles (Record no. 7780)
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| 000 -LEADER | |
|---|---|
| fixed length control field | a |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20181205112221.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 181205b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | AIKTC-KRRC |
| Transcribing agency | AIKTC-KRRC |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 6685 |
| Author | Sonkar, S. |
| 245 ## - TITLE STATEMENT | |
| Title | Synthesis, characterization and antimalarial-antimicrobial studies of some novel derivatives of chloroquinoline base pyrazoles |
| 250 ## - EDITION STATEMENT | |
| Volume, Issue number | Vol. 55 (02) |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Mumbai |
| Name of publisher, distributor, etc. | Indian Drug Manufacture's Association - IDMA |
| Year | 2018 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Pagination | 7-14 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | The prime aim of the present investigation was to synthesize a series of novel derivatives of pyrazole based quinolines by the reaction of substituted chalcones and characterized them by their physical and spectral data. All the compounds were confirmed by TLC and melting point. The structures of the synthesized compounds have been established on the basis of IR, 1 H NMR, EIMS spectral analysis and elemental analysis. The synthesized target compounds were screened for their anti-malarial activity using Vero cell line (C1008; Monkey kidney fibroblast) against Plasmodium falciparum (3D7 strain) with the standard and SI was measured by using IC50 and CC50 of tested compounds. Additionally, the synthesized compounds were evaluated for their in vitro antimicrobial activity against two each gram positive, gram negative and antifungal strains |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 4639 |
| Topical term or geographic name entry element | PHARMACEUTICS |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 6687 |
| Co-Author | Pathak, D. |
| 773 0# - HOST ITEM ENTRY | |
| Place, publisher, and date of publication | Mumbai Indian Drug Manufactures Association |
| Title | Indian drugs |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Articles Abstract Database |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Home library | Current library | Shelving location | Date acquired | Total Checkouts | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | School of Pharmacy | School of Pharmacy | Archieval Section | 28/03/2019 | 2018011 | 19/06/2019 | 28/03/2019 | Articles Abstract Database |