Cutaneous adverse drug reactions with fixed-dose combinations: Special reference to self-medication and preventability (Record no. 8349)

MARC details
000 -LEADER
fixed length control field a
003 - CONTROL NUMBER IDENTIFIER
control field OSt
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20190514115929.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 190226b xxu||||| |||| 00| 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency AIKTC-KRRC
Transcribing agency AIKTC-KRRC
100 ## - MAIN ENTRY--PERSONAL NAME
9 (RLIN) 7677
Author Tripathy, Ratikanta
245 ## - TITLE STATEMENT
Title Cutaneous adverse drug reactions with fixed-dose combinations: Special reference to self-medication and preventability
250 ## - EDITION STATEMENT
Volume, Issue number Vol. 50(4), July-August
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Mumbai
Year 2018
Name of publisher, distributor, etc. Wolter Kluwer
300 ## - PHYSICAL DESCRIPTION
Pagination 192-196
520 ## - SUMMARY, ETC.
Summary, etc. To identify the association of cutaneous adverse drug reactions (CADRs) with use of fixed-dose combinations (FDCs) and to compare the occurrence of preventable CADRs between self-medication and prescribed medication of FDCs. PATIENTS AND METHODS: All cases of suspected CADRs with the use of FDCs were collected, and causality assessment was carried out using the WHO UMC scale. The burden of CADRs on self-medication and prescribed medication was found out. Preventability status was analyzed by Schumock and Thornton Criteria and compared between self-medication and prescribed medication. RESULTS: A total of 74 CADRs were detected; 68.91% were detected with antimicrobial and 31.09% with nonsteroidal anti-inflammatory drug-based FDCs. Fluoroquinolones + nitroimidazole was the most commonly suspected medications. Majority of CADRs (44.59%) were fixed-drug eruptions, which was significantly higher than others (P = 0.002). Analysis of preventability showed that there was a significantly higher occurrence of definitely preventable CADRs in self-medication group (40%) in comparison to prescribed group (6.81%), P = 0.028. CONCLUSIONS: Self-medication with FDCs is quite common and associated with a higher rate of preventable CADRs in comparison to that in prescribed medication. <br/><br/><br/>
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
9 (RLIN) 4774
Topical term or geographic name entry element PHARMACOLOGY
700 ## - ADDED ENTRY--PERSONAL NAME
9 (RLIN) 7678
Co-Author Pattnaik, Kali Prasad
700 ## - ADDED ENTRY--PERSONAL NAME
9 (RLIN) 7679
Co-Author Dehury, Suhasini
773 0# - HOST ITEM ENTRY
Place, publisher, and date of publication Andheri - Mumbai Wolters Kluwer India Private Limited
Title Indian Journal of Pharmacology
International Standard Serial Number 0253-7613
856 ## - ELECTRONIC LOCATION AND ACCESS
Link text Click here
URL http://www.ijp-online.com/article.asp?issn=0253-7613;year=2018;volume=50;issue=4;spage=192;epage=196;aulast=Tripathy;type=0
942 ## - ADDED ENTRY ELEMENTS (KOHA)
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Koha item type Articles Abstract Database
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    Dewey Decimal Classification     School of Pharmacy School of Pharmacy Archieval Section 29/03/2019   2018276 19/06/2019 29/03/2019 Articles Abstract Database
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