Antimicrobial profiles, antidiarrheal and antipyretic capacities of phenol, acid rich-fractions from ximenia america I.., (olacaceae) in wistar albino rats (Record no. 8448)
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| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20190315092434.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 190307b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | AIKTC-KRRC |
| Transcribing agency | AIKTC-KRRC |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 7878 |
| Author | Kiessoun, Konate |
| 245 ## - TITLE STATEMENT | |
| Title | Antimicrobial profiles, antidiarrheal and antipyretic capacities of phenol, acid rich-fractions from ximenia america I.., (olacaceae) in wistar albino rats |
| 250 ## - EDITION STATEMENT | |
| Volume, Issue number | Vol. 10(10), July-August |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | M. P. |
| Name of publisher, distributor, etc. | Innovare Academic Sciences Pvt Ltd |
| Year | 2018 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Pagination | 62-68 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Objective: The present study aim to evaluate antimicrobial and antidiarrheal activities of phenol acid-rich fractions of roots from Ximeniaamericana L. , in animal models in order to confirm the ethnomedicinal use of Ximenia Americana L., roots. Methods: In vitro antibacterial (Minimum inhibitory concentration (MIC), Minimum bactericidal concentration (MBC) and time-kill studies) of phenol-rich fractions of roots fromXimenia americana L., was assessed using eight bacteria strains (Gram-negative). The anti-diarrheal activity was evaluated using castor using castor oil induced diarrhea whereas Anti-secretory activity was investigated using castor oil-induced enteropoolingassay examined in animal models respectively. Results: All test bacteria were susceptible to the phenol-rich fractions. Time-kill results showed that after 5 h exposition there was no viablemicroorganism in the initial inoculum. Moreover, phenol acid-rich fractions of roots (100-200 and 300 mg/kg, p. o.) produced dose-dependent and significant (p<0.05-0.001) protection of rats against castor oil-induced diarrhea, and delayed gastric emptying. Phenol acid-rich fractions of roots, dose-dependently and significantly (p<0.05-0.001) delayed the onset of castor oil induced diarrhea, decreased the frequency of defecation, and reduced the severity of diarrhea in the rats. Phenol acid-rich fractions caused dose-related inhibition of castor-oil-induced enteropooling in rats. Conclusion: The data analysis indicates that the tested of phenol-rich fractions has significant effects when compared with the standard antibiotic. These results, therefore, justify the traditional use of Ximenia americanaL. About antidiarrheal activity, the findings of this study indicate that phenol acid-rich fraction possesses antidiarrheal property in rats. These findings .... |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 4639 |
| Topical term or geographic name entry element | PHARMACEUTICS |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 7879 |
| Co-Author | Roland, Meda Nag Tiero |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 7880 |
| Co-Author | Mamounata, Diao |
| 773 0# - HOST ITEM ENTRY | |
| International Standard Serial Number | 0975 – 1491 |
| Title | International journal of pharmacy and pharmaceutical science |
| Place, publisher, and date of publication | Bhopal Innovare Academic Sciences Pvt Ltd |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| URL | https://innovareacademics.in/journals/index.php/ijpps/article/view/25485/15889 |
| Link text | Click here |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Articles Abstract Database |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Home library | Current library | Shelving location | Date acquired | Total Checkouts | Barcode | Date last seen | Price effective from | Koha item type |
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| Dewey Decimal Classification | School of Pharmacy | School of Pharmacy | Archieval Section | 30/03/2019 | 2018418 | 19/06/2019 | 30/03/2019 | Articles Abstract Database |