Comparative evaluation of in vitro antioxidant and in vivo hepatooprotective activities of ethanolic leaf and root extracts of cleome gynandra (Record no. 9040)
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| 000 -LEADER | |
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| fixed length control field | a |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20190520103302.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 190520b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | AIKTC-KRRC |
| Transcribing agency | AIKTC-KRRC |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 6961 |
| Author | Ravishankar, K. |
| 245 ## - TITLE STATEMENT | |
| Title | Comparative evaluation of in vitro antioxidant and in vivo hepatooprotective activities of ethanolic leaf and root extracts of cleome gynandra |
| 250 ## - EDITION STATEMENT | |
| Volume, Issue number | Vol. 56(04), April |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Mumbai |
| Name of publisher, distributor, etc. | Indian Drug Manufacturers Association |
| Year | 2019 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Pagination | 50-56p. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | In vitro antioxidant and in vivo hepatoprotective activities of Cleome gynandra ethanolic leaf and root extracts were assessed. In vitro antioxidant activity was carried by DPPH, Nitric oxide, hydroxyl radical and phosphomolybdenum assays. Hepatoprotective activity was evaluated by Carbon tetrachloride (CCl4) induced hepatotoxicity in albino rats.The animals were divided into seven groups (Four test groups - Ethanolic Leaf and Root Extracts of Cleome gynandra of 100 mg/kg and 200 mg/kg, standard silymarin (100 mg/kg), toxic control-carbon tetrachloride and vehicle). On the eight day, the blood was collected and parameters like serum glutamic oxaloacetic transaminase (SGOT), Serum glutamic pyruvic transaminase (SGPT), Alkaline phosphatase (ALP) and Total bilirubin (TB) were estimated. Significant antioxidant status with good IC50 values similar to standard ascorbic acid was obtained. A significant decrease in liver enzymes was observed in test groups comparable to silymarin. From the results obtained, ethanolic leaf extract has contributed better hepatoprotection compared with root extract in experimental rats. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 5021 |
| Topical term or geographic name entry element | DRUG STORE MANAGEMENT |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 8628 |
| Co-Author | Lakshmi Prasanna, Y. V. V. M. |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 6962 |
| Co-Author | Kiranmayi, G. V. N. |
| 773 0# - HOST ITEM ENTRY | |
| Title | Indian drugs |
| Place, publisher, and date of publication | Mumbai Indian Drug Manufactures Association |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| URL | https://www.indiandrugsonline.org/issuesarticle-details?id=OTIz |
| Link text | Click here |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Articles Abstract Database |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Home library | Current library | Shelving location | Date acquired | Total Checkouts | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | School of Pharmacy | School of Pharmacy | Archieval Section | 20/05/2019 | 2018529 | 19/06/2019 | 20/05/2019 | Articles Abstract Database |