HEALTH- RELATED QUALITY OF L IFE IN EARLY BREAST CANCER PATIENTS WITH HORMON E RESPONSIVE
Publication details: M P Innovare Academic Sciences Pvt Ltd 2018Edition: Vol.10(12)Description: 47-49pSubject(s): Online resources: In: International journal of pharmacy and pharmaceutical scienceSummary: Objective : The management of early breast cancer (EBC) is performed with a series of treatments consisting of surgery and systemic therapy, along with long -term endocrine therapy for hormone responsive. The treatment generates a high illness effect that will affect the life quality of EBC patients. Th e objective of this study was to measure EBC patients ’ quality of life after undergo ing the treatment. Method s: A cross -sectional study was conducted by interviewing EBC patients using EQ -5D -5L instrument at private hospital s in Yogyakarta and Semarang , Indonesia . The EBC patients were women aged 18 -60 y who ha d undergone surgery in 2010 -2013 and receive d endocrine ther apy. Result s : Of the 71 patients identified , 45 patients were in disease -free survival (DFS) state , 8 patients were in locoregional recurrence (LR), and 18 patients were in metastasis (M) state . Mobil ity and self -care problems occurred in patients who had metastasis (4. 23%). The p roblem of usual activities occur ed in patients who had recurrence (22. 54%). Most of the patients (84.51%) had pain problem , and all patients had an anxiety problem. The mean utility score (SD) in DFS patient s was 0.841 (0.052) , in LR patients w as 0.758 (0.092) , and in patients who had metastasis was 0. 653 (0.104). The mean scores of EQ -5D VAS (SD) for EBC patients in DFS, LR and M health state were 86.56 (6.29), 81.88 (5.30), and 69.17 (5.75), respectively. Concl usio n : The health states of EBC significantly affect HRQOL of patients . Efforts should be made to improve the quality of life of EBC patie nts especially in terms of pain and anxiety reduction.| Item type | Current library | Status | Barcode | |
|---|---|---|---|---|
|  Articles Abstract Database | School of Pharmacy Archieval Section | Not for loan | 2020955 | 
                                                    
                                                        Objective
:
The management of early breast cancer (EBC) is performed with a series of treatments consisting of
 surgery and systemic therapy, along 
with  long
-term  endocrine  therapy  for  hormone  responsive.  
The  treatment  generates
  a  high  illness  effect  that  will  affect  the  
life 
quality  of  EBC  
patients. 
Th
e objective of this study
 was
 to measure EBC patients
’ quality of life
 after 
undergo
ing
 the 
treatment. 
Method
s: A  cross
-sectional study was conducted by interviewing EBC patients using 
EQ
-5D
-5L
 instrument
  at 
private  hospital
s  in 
Yogyakarta
 and
Semarang
, Indonesia
. The EBC patients were women aged 18
-60 y
 who ha
d undergone surgery in 2010
-2013 and receive
d endocrine ther
apy. 
Result
s
:
Of  the  71  patients  identified
,  45  patients  were  in  disease
-free
  survival  (DFS)
  state
,  8  patients  were  in  locoregional  recurrence  (LR),  and  18  
patients 
were
 in metastasis
 (M)
 state
. Mobil
ity and self
-care problems occurred in
 patients 
who had
 metastasis (4.
23%). 
The p
roblem of 
usual activities
occur
ed
 in patients who had
 recurrence
 (22.
54%). Most of 
the 
patients (84.51%) had pain
 problem
, and
 all patients had an 
anxiety
 problem. The mean 
utility score (SD)
 in DFS patient
s was
 0.841
 (0.052)
, in LR patients w
as
 0.758
 (0.092)
, and in patients who had metastasis was 0.
653
 (0.104).
 The mean
scores
 of EQ
-5D VAS (SD) for EBC patients in DFS, LR and M health state 
were 86.56
 (6.29), 81.88 (5.30), 
and 
69.17 (5.75), respectively. 
Concl
usio
n
:
The 
health  states  of  EBC  significantly  affect  HRQOL
  of 
patients
. Efforts  should  be  made  to  improve  the  quality  of  life  of  EBC  patie
nts 
especially in terms of pain
 and anxiety reduction.
                                                    
                                                
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