HVU is a multidisciplinary public local university, so they have specific characteristics to deploy e-learning in the general context of Vietnam. The pressure of implementing e-learning based on the appearance of Covid-19 leads to surprise and unexpected successes. The amount of work after Covid-19 occurred is many times more than before 2019, including implementing an e-learning system and the use of related users such as administrators, lecturers, and students. The research objective is to introduce the process of applying e-learning in HVU to the stakeholders. The experimental results are conducted by 508 surveys on students and 62 surveys on lecturers. The surveyed information includes (1) The interaction of students when using MS Teams; (2) The feedback from students when using HVU LMS; and (3) The habits of the lecturers when using elearning tools. All of those results verify the reached goal of the e-learning implementation of HVU.