Design, optimization, and in vitro evaluation of orally disintegrating tablets containing amlodipine besylate
Publication details: Banagalore Association of Pharmaceutical Teachers of India (APTI) 2024Edition: Vol.58(4), Oct-DecDescription: 1205-1214pSubject(s): Online resources: In: Indian journal of pharmaceutical education and researchSummary: In this study, it was aimed to prepare orally disintegrating tablet formulations of amlodipine besylate by applying the experimental design. Materials and Methods: A face-centered, central composite 32 full factorial design was applied to evaluate the effects of filler ratio (MAN: MCC; X1) and super disintegrant percentage (SSG; X2) on the critical tablet characteristics such as tensile strength (Y1), disintegration time (Y2) and dissolution rate (5th min) (Y3).| Item type | Current library | Status | Barcode | |
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School of Pharmacy Archieval Section | Not for loan | 2025-0298 |
In this study, it was aimed to prepare orally disintegrating tablet formulations of amlodipine besylate by applying the experimental design.
Materials and Methods:
A face-centered, central composite 32 full factorial design was applied to evaluate the effects of filler ratio (MAN: MCC; X1) and super disintegrant percentage (SSG; X2) on the critical tablet characteristics such as tensile strength (Y1), disintegration time (Y2) and dissolution rate (5th min) (Y3).
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