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Evaluation of in vitro anti-oxidant and anti-inflammatory activity of ethanolic extract of hevea brasiliensis roots

By: Publication details: Mandsaur B.R. Nahata Smriti Sansthan 2024Edition: Vol.18(3), Jul-SepDescription: 190-194pSubject(s): Online resources: In: International journal of green pharmacySummary: This study examines the in vitro antioxidant and anti-inflammatory activities of the ethanolic extract of Hevea brasiliensis roots. The potential medical benefits of H. brasiliensis, a plant farmed largely for latex production, are being investigated. To create the crude extract, the roots were collected, dried, and then extracted using ethanol. After being dried, the resulting extracts underwent a preliminary phytochemical screening procedure 1,1-Diphenyl-2-picrylhydrazyl (DPPH) radical scavenging tests was used to measure antioxidant activity. DPPH studies showed that the extract had a substantial ability to neutralize free radicals, indicating significant antioxidant activity. The protein denaturation inhibition assay was used to assess the anti-inflammatory properties. The extract showed a significant reduction in the denaturation of proteins. The ethanolic extract of H. brasiliensis roots has significant antioxidant and anti-inflammatory properties, indicating its potential as a natural source of therapeutic agents for oxidative stress and inflammation-related conditions. More in vivo studies and compound isolation are needed to fully explore the medicinal potential of H. brasiliensis roots.
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This study examines the in vitro antioxidant and anti-inflammatory activities of the ethanolic extract of Hevea
brasiliensis roots. The potential medical benefits of H. brasiliensis, a plant farmed largely for latex production,
are being investigated. To create the crude extract, the roots were collected, dried, and then extracted using
ethanol. After being dried, the resulting extracts underwent a preliminary phytochemical screening procedure
1,1-Diphenyl-2-picrylhydrazyl (DPPH) radical scavenging tests was used to measure antioxidant activity. DPPH
studies showed that the extract had a substantial ability to neutralize free radicals, indicating significant antioxidant
activity. The protein denaturation inhibition assay was used to assess the anti-inflammatory properties. The extract
showed a significant reduction in the denaturation of proteins. The ethanolic extract of H. brasiliensis roots has
significant antioxidant and anti-inflammatory properties, indicating its potential as a natural source of therapeutic
agents for oxidative stress and inflammation-related conditions. More in vivo studies and compound isolation are
needed to fully explore the medicinal potential of H. brasiliensis roots.

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