Solubility enhancement techniques play a pivotal role in overcoming challenges associated with poorly soluble drugs,
thus improving their bioavailability and therapeutic efficacy. This abstract provides a concise overview of various
strategies employed in pharmaceutical formulations to enhance drug solubility. Techniques such as Micronization,
solid dispersion, super critical fluid technique, cryogenic technique, kneading, solvent evaporation, co-precipitation
method, precipitation, high pressure homogenization, SEDDS, liquid solid technique, Sonocrystallization,
nanotechnology, prodrug approach are discussed. Understanding the principles and applications of these techniques
is essential for formulators to develop effective drug delivery systems. By employing these strategies individually or
in combination, researchers aim to address solubility issues and advance drug development in the pharmaceutical
industry.