Spedding, Michael  <br/><br/>
Aging, VO2 max, entropy, and COVID‑19 

 - Vol.54(1), Jan-Feb 
 - Mumbai  Wolter Kluwer  2022 
 - 58-62p. 
<br/><br/> The decline in human performance with age at 5000 m, an athletic event requiring high VO2 max, is<br/>remarkably precise, and unavoidable, and related to entropy, even at an individual level. Women and<br/>men show an identical age‑related decline, up to ~100 years old. The precision of the decline shows<br/>the limitations for therapy of aging. Mortality incidence for COVID‑19 shows a similar relationship. We<br/>propose that initial VO2 max has a critical role in COVID sensitivity because of the direct relationship<br/>of disease severity with oxygen use, and the parallel decline in aging. 
<br/><br/><label>Subjects--Topical Terms: </label><br/>PHARMACOLOGY