Sevinç, Şahbaz <br/><br/>
Design, optimization, and in vitro evaluation of orally disintegrating tablets containing amlodipine besylate 

 - Vol.58(4), Oct-Dec 
 - Banagalore  Association of Pharmaceutical Teachers of India (APTI)  2024 
 - 1205-1214p. 
<br/><br/> In this study, it was aimed to prepare orally disintegrating tablet formulations of amlodipine besylate by applying the experimental design.<br/>Materials and Methods:<br/><br/>A face-centered, central composite 32 full factorial design was applied to evaluate the effects of filler ratio (MAN: MCC; X1) and super disintegrant percentage (SSG; X2) on the critical tablet characteristics such as tensile strength (Y1), disintegration time (Y2) and dissolution rate (5th min) (Y3).<br/> 
<br/><br/><label>Subjects--Topical Terms: </label><br/>PHARMACEUTICS