This study examines the impact of deicers on the compressive strength and microstructure of concrete at ambient temperatures in sub-zero regions. After seven days of curing in plain water, concrete specimens were exposed to four types of deicer chemical solutions: sodium chloride, sodium acetate, calcium nitrate, and urea at concentrations of 3, 6 , and 9 %. The specimens were then tested for compressive strength after 14, 28, and 90 days of exposure. The compressive strength of concrete specimens exposed to sodium chloride, sodium acetate, and urea decreased proportionally with both deicer concentration and exposure duration. In contrast, the compressive strength of concrete specimens exposed to calcium nitrate solutions increased. Sodium acetate, which exhibited the most detrimental effect, reduced the compressive strength of concrete by a maximum of 30.79 % at a 9 % concentration. Conversely, exposure to calcium nitrate increased the compressive strength of concrete by 17 % at a 3 % concentration. The changes in compressive strength were attributed to the formation of new products and alterations in the microstructure morphology of the concrete due to deicer exposure, as evidenced by Field Emission – Scanning Electron Microscopy (FE-SEM) micrographs. The relative intensity of hydrated cement products in concrete specimens exposed to deicer solutions was determined through X-Ray Diffraction (XRD) analysis and compared to control concrete specimens. In conclusion, among the deicers examined, calcium nitrate was the only one found to have a positive impact on concrete compressive strength.