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008 160914s2017 gw | s |||| 0|eng d
020 _a9783319414751
040 _cAIKTC-KRRC
041 _aENG
072 7 _aMQW
_2bicssc
072 7 _aTEC059000
_2bisacsh
072 7 _aMQW
_2thema
082 0 4 _a610.28
_223
245 1 0 _aBiomechanics: Trends in Modeling and Simulation
_h[electronic resource] /
250 _a1st ed. 2017.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2017.
300 _aIX, 316 p. 129 illus., 63 illus. in color.
_bCard Paper
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aStudies in Mechanobiology, Tissue Engineering and Biomaterials,
_x1868-2006 ;
_v20
520 _aThe book presents a state-of-the-art overview of biomechanical and mechanobiological modeling and simulation of soft biological tissues. Seven well-known scientists working in that particular field discuss topics such as biomolecules, networks and cells as well as failure, multi-scale, agent-based, bio-chemo-mechanical and finite element models appropriate for computational analysis. Applications include arteries, the heart, vascular stents and valve implants as well as adipose, brain, collagenous and engineered tissues. The mechanics of the whole cell and sub-cellular components as well as the extracellular matrix structure and mechanotransduction are described. In particular, the formation and remodeling of stress fibers, cytoskeletal contractility, cell adhesion and the mechanical regulation of fibroblast migration in healing myocardial infarcts are discussed. The essential ingredients of continuum mechanics are provided. Constitutive models of fiber-reinforced materials with an emphasis on arterial walls and the myocardium are discussed and the important influence of residual stresses on material response emphasized. The mechanics and function of the heart, the brain and adipose tissues are discussed as well. Particular attention is focused on microstructural and multi-scale modeling, finite element implementation and simulation of cells and tissues.
650 0 _aMechanical Engineering
_94626
653 _aMathematical Modeling and Industrial Mathematics.
653 _aTheoretical and Applied Mechanics.
653 _aBiomaterials.
653 _aBiological and Medical Physics, Biophysics.
700 1 _aHolzapfel, Gerhard A.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aOgden, Ray W.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
710 2 _aSpringerLink (Online service)
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9783319414737
776 0 8 _iPrinted edition:
_z9783319414744
776 0 8 _iPrinted edition:
_z9783319823645
830 0 _aStudies in Mechanobiology, Tissue Engineering and Biomaterials,
_x1868-2006 ;
_v20
856 4 0 _uhttps://doi.org/10.1007/978-3-319-41475-1
_zClick here to access eBook in Springer Nature platform. (Within Campus only.)
942 _cEBOOKS
_2ddc