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040 _aAIKTC-KRRC
_cAIKTC-KRRC
100 _914727
_a Nguyen-Le, Duy
245 _aExtraction and Evaluation of Lipid Entrapment Ability of Ocimum basilicum L. Seed Mucilage
250 _aVol.55(3), Jul-Sep
260 _aBanagalore
_bAssociation of Pharmaceutical Teachers of India (APTI)
_c2021
300 _a880-887p.
520 _aBackground: Overweight, obesity is a serious health problem worldwide and has been becoming an epidemic recently due to the rapid growth of its prevalence. The consequences of obesity are not only its related diseases such as diabetes and cardio vascular disease, but also the effects on global socio-economic. Aim: In this study, we obtained and evaluated characteristics of Ocimum basilicum L. (OB) seed mucilage which fit for developing a weight control product through several characteristics such as swelling index, stability, toxicity and lipid adsorption/absorption from different sources. All of the statistical analysis was done by Graphpad prism using unpaired t-test. Results: The extraction yield by physical method was 10.17% and the swelling index of dried mucilage was 20.6 times higher than the initial weight. The drying temperature affected only on the mucilage through the increasing of reducing sugars concentration. The OB mucilage showed neither cytotoxicity on NIH-3T3 cells nor chronic/acute toxicity on mice. Last but not least, OB mucilage was able to absorb/adsorb lipid from different lipid sources. Conclusion: OB mucilage was proven to be a high potential source of polysaccharide for developing weight treatment products.
650 0 _94639
_aPHARMACEUTICS
700 _914728
_a Nguyen, Cao-Tri
773 0 _x0019-5464
_dBengluru Association of Pharmaceutical Teachers of India (APTI)
_tIndian journal of pharmaceutical education and research
856 _uhttps://www.ijper.org/sites/default/files/IndJPhaEdRes-55-3-880.pdf
_yClick here
942 _2ddc
_cAR