000			a
999			_c15553 _d15553
003			OSt
005			20211123100644.0
008			211123b xxu||||| |||| 00| 0 eng d
040			_aAIKTC-KRRC _cAIKTC-KRRC
100			_914748 _a Shirke, Monika
245			_aSynthesis, Characterization and Pharmacological Evaluation of Biphenyl Based 4-Thiazolidinones
250			_aVol.55(2), Apr-Jun
260			_aBanaglore _bAssociation of Pharmaceutical Teachers of India (APTI) _c2021
300			_a363-373p.
520			_aBackground: Biphenyl based 4-thiazolidinones are found to possess a wide range of activities resulting in their synthesis. Methods: Eight molecules (VIIa-VIIh) were profoundly synthesized using four step procedures. These 4-thiazolidinone derivatives were characterized by elemental analysis (CHN) and spectral (IR and 1H NMR) analysis. All the compounds were evaluated for their in vitro antimicrobial activity against one Gram negative strain (Escherichia coli) and two Gram positive strains (Bacillus subtilis and Staphylococcus aureus) and two fungal strains (Candida albicans and Aspergillus niger). Results: The results of antimicrobial studies revealed that compounds (VIIg) possessed moderate antifungal activity and compounds (VIIc and VIIe) showed good antibacterial activity against fungal and bacterial strain respectively. Conclusion: Compounds containing electron withdrawing groups (-NO2, -CI, -Br) on the aromatic ring showed improved antimicrobial activity.
650		0	_94639 _aPHARMACEUTICS
700			_914749 _aGangthade, Monali
773	0		_x0019-5464 _dBengluru Association of Pharmaceutical Teachers of India (APTI) _tIndian journal of pharmaceutical education and research
856			_uhttps://www.ijper.org/sites/default/files/IndJPhaEdRes-55-2-363.pdf _yClick here
942			_2ddc _cAR