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040 _aAIKTC-KRRC
_cAIKTC-KRRC
100 _917578
_aBharkatiya, Meenakshi
245 _aStrategies for the suitability of self-assembled supramolecular polymersomes in drug delivery and diagnostics
250 _aVol.56(3), Jul-Sep
260 _aKarnataka
_bAssociation of Pharmaceutical Teachers of India (APTI)
_c2022
300 _a608-617p.
520 _aAmphiphilic copolymers which can self-organize into distinct nano vesicles comprising of hydrophilic core and a hydrophobic bilayer membrane with innumerable morphologies have wide applications ranging from cell mimics to diagnostics. The flexibility to control the size, shape, morphology, functionality and surface properties makes polymersomes widely acceptable. The suitability of these systems for various biomedical applications exhilarated because of its robust responsiveness to both internal and external stimuli at the site of interest. The biodegradability with lesser toxicity adds up to its acceptability as an innate cargo molecule. A large share of research works published on the polymersomes in recent years showcase this vesicle as a future device of choice for targeted drug delivery and bio imaging. But the effectiveness of these systems meticulously relays on the precise engineering of physical, morphological and surface characteristics supported by thorough understanding on the various aspects of its designing. With an intention of accelerating multiple dimensions of polymersome research, this article focuses on recapitulating those controllable essential attributes of polymersomes. It also reveals how changes in these variables contribute to polymersomes becoming an important potential freight moiety for a variety of biomedical relevence.
650 0 _94639
_aPHARMACEUTICS
700 _917579
_aSharma, Komal
773 0 _tIndian journal of pharmaceutical education and research
_dBengluru Association of Pharmaceutical Teachers of India (APTI)
_x0019-5464
856 _uhttps://ijper.org/sites/default/files/IndJPhaEdRes-56-3-608.pdf
_yClick here
942 _2ddc
_cAR