| 000 | a | ||
|---|---|---|---|
| 999 |
_c17332 _d17332 |
||
| 003 | OSt | ||
| 005 | 20220826092014.0 | ||
| 008 | 220826b xxu||||| |||| 00| 0 eng d | ||
| 040 |
_aAIKTC-KRRC _cAIKTC-KRRC |
||
| 100 |
_917605 _aAkkoyun, H. Turan |
||
| 245 | _aEffects of arbutin on fatty acid levels of erythrocyte and serum in wistar albino rats treated with potassium bromate | ||
| 250 | _aVol.56(3), Jul-Sep | ||
| 260 |
_aKarnataka _bAssociation of Pharmaceutical Teachers of India (APTI) _c2022 |
||
| 300 | _a740-747p. | ||
| 520 | _aBackground: In the presented study; the Effects of Arbutin (ARB) on the Rat Erythrocyte and serum fatty acid profile which is exposed to potassium bromate (KBrO3 ) were investigated. Materials and Methods: In this study, 32 Wistar albino rats weighing 250-300 g were used divided into 4 groups. Groups 1: control, group 2: KBrO3 (single dose 100 mg / kg gavage), group 3: ARB (50 mg / kg / day (ip) for 5 days), group 4: KBrO3 + ARB. At the end of the 5th day, alteration of fatty acid profile in erythrocyte and serum of rats in all groups was examined. Results: Rat serum essential fatty acid; palmitic acid (C16:0), myristic acid (C14:0), stearic acid (C18:0), oleic acid (C18:1), linoleic acid (C18:2), erythrocyte major fatty acids; palmitic acid (C16:0), myristic acid (C14:0), stearic acid (C18:0), oleic acid (C18:1), linoleic acid (C18:2), arachidic acid (C20:0), eicosenoic acid (C20:1), and lignoceric acid (C24:0). In addition, in our studied serum and erythrocytes; Total monounsaturated fatty acids (MUFA) varied between 8.91 ± 0.53- 11.71 ± 2.55 and 33.71 ± 2.12- 37.11 ± 2.12, respectively. It was determined that total polyunsaturated fatty acids (PUFA) varied between 5.90 ± 1.29- 9.96 ± 1.18 and 14.72 ± 3.66- 22.13 ± 4.82, respectively. Conclusion: In our study, alterations in fatty acid contents were observed, and results suggesting that arbutine affects the enzymes involved in Fatty acid metabolism and has an effect on fatty acid amounts. | ||
| 650 | 0 |
_94639 _aPHARMACEUTICS |
|
| 700 |
_917606 _aAydın, Sevinç |
||
| 773 | 0 |
_x0019-5464 _dBengluru Association of Pharmaceutical Teachers of India (APTI) _tIndian journal of pharmaceutical education and research |
|
| 856 |
_uhttps://www.ijper.org/sites/default/files/IndJPhaEdRes-56-3-740.pdf _yClick here |
||
| 942 |
_2ddc _cAR |
||