000			a
999			_c17350 _d17350
003			OSt
005			20220829094525.0
008			220829b xxu||||| |||| 00| 0 eng d
040			_aAIKTC-KRRC _cAIKTC-KRRC
100			_917638 _aGawade, Shivaji Prataprao
245			_aPerspectives of presynaptic autoreceptors and presynaptic heteroreceptors in the mechanism of neurotransmission
250			_aVol.56(2), Apr-June
260			_aKarnataka _bAssociation of Pharmaceutical Teachers of India (APTI) _c2022
300			_a329-346p.
520			_aThe presynaptic autoreceptors and / or presynaptic heteroreceptors of the principal neurotransmitters involved in the release mechanism of neurotransmission have been identified employing various experimental models, based on receptor types / receptor subtypes and it’s stimulatory or inhibitory functions. The pharmacological, neurophysiological, neurobiochemical in vivo or in vitro insect, animal or human prototype experimental models were selected from the exhaustive search of literature published in standard journals using, Google search engine, to identify the presynaptic autoreceptors or presynaptic heteroreceptors. The complexity of neuronal function in nervous system is based on the expression of presynaptic autoreceptors controlling / regulating the release and that of presynaptic heteroreceptors activated by the neurotransmitter / modulator released from other axon terminal communicated inter/ intraneuronally. In the present review, eight types of prominent presynaptic auto or heteroreceptors of seven neurotransmitters of central and peripheral nervous system namely cholinergic muscarinic, cholinergic nicotinic, adrenergic, serotonergic, dopaminergic, histaminergic, glutaminergic and GABArgic and their subtypes were classified according to stimulatory or inhibitory functions and explained on the basis of prototype experimental in vitro / in vivo tissue models.
650		0	_94639 _aPHARMACEUTICS
773	0		_tIndian journal of pharmaceutical education and research _x0019-5464 _dBengluru Association of Pharmaceutical Teachers of India (APTI)
856			_uhttps://www.ijper.org/sites/default/files/IndJPhaEdRes-56-2-329.pdf _yClick here
942			_2ddc _cAR