000			a
999			_c17351 _d17351
003			OSt
005			20220829095451.0
008			220829b xxu||||| |||| 00| 0 eng d
040			_aAIKTC-KRRC _cAIKTC-KRRC
100			_917639 _aNamdev, Bhavesh
245			_aBrief review on solubility enhancement technique: hydrotropy
250			_aVol.56(2), Apr-Jun
260			_aKarnataka _bAssociation of Pharmaceutical Teachers of India (APTI) _c2022
300			_a347-355p.
520			_aIn this review we have elaborated about number of hypothesis postulated to understand the mechanism of hydrotropic agents, although majority of the postulated hypothesis haven’t justified the solubility enhancement mechanism. Further to it the articles focuses upon the parameters affecting enhancement of solubilizing ability. Hydrotropes are extensively used in drug solubilization, extraction agents for various phytoconstituents, separation agent used for pharmaceutical analysis, as well as for increasing the rate and yield of a chemical reaction due to their unique features. Because of this, hydrotropic solutions possess high industrial demand. While mixed hydrotropy is mostly used in enhancement of solubility, extraction of phytoconstituents and separation by the use of more than one hydrotropic agent. This review article also highlights the applications and future prospects with the employment of hydrotropes and hydrotropic agents in novel drug delivery or parental or oral or tropical systems to enhance solubility profile the drugsare also discussed.
650		0	_94639 _aPHARMACEUTICS
700			_917640 _aVenkatachalam, Senthil
773	0		_tIndian journal of pharmaceutical education and research _x0019-5464 _dBengluru Association of Pharmaceutical Teachers of India (APTI)
856			_uhttps://www.ijper.org/sites/default/files/IndJPhaEdRes-56-2-347.pdf _yClick here
942			_2ddc _cAR