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040			_aAIKTC-KRRC _cAIKTC-KRRC
100			_923112 _aKalita, Deepjyoti
245			_aDrug resistance profile in postbiliary and gastrointestinal surgical-site infection cases from a tertiary care hospital
250			_aVol.55(6), Nov-Dec
260			_aMumbai _bWolter Kluwer _c2023
300			_a399-404p.
520			_aIn the developing world, surgical-site infection (SSI)-associated pathogens are becoming more drug resistant implicating higher morbidity and management cost. Here, we tried to analyze the drug resistance pattern in our SSI-related isolates. Over 2 years, 191 clinically diagnosed SSIs (postbiliary tract and postgastrointestinal surgery) were included, and wound swabs were processed by conventional aerobic and anaerobic culture. Antibiotic minimum inhibitory concentration (MIC) was determined by the Epsilometer testing. Multidrug-resistant phenotypes were detected as per guidelines. The rate of SSI was 5.3% with Klebsiella, Staphylococcus, and Pseudomonas, growing predominantly, and no anaerobe detectable. About 19.4% of Staphylococcus aureus were methicillin-resistant S. aureus, and one-third of them had raised macrolide MIC. About 58.2% of Enterobacteriaceae isolates were extended-spectrum beta-lactamase producers. Isolates with raised meropenem MIC were observed. Antibiotic-resistant level in SSI cases is alarmingly high, and in susceptible strains, MIC is approaching the resistant level. Urgent corrective action is an emergency necessity.
650		0	_94774 _aPHARMACOLOGY
700			_923113 _aRajbangshi, Madhab Chandra
773	0		_tIndian Journal of Pharmacology _x0253-7613 _dAndheri - Mumbai Wolters Kluwer India Private Limited
856			_uhttps://journals.lww.com/iphr/fulltext/2023/55060/drug_resistance_profile_in_postbiliary_and.8.aspx _yClick here
942			_2ddc _cAR