000			a
999			_c21887 _d21887
003			OSt
005			20241210143218.0
008			241210b xxu||||| |||| 00| 0 eng d
040			_aAIKTC-KRRC _cAIKTC-KRRC
100			_924746 _aGayen, Tirthankar
245			_aDolutegravir-induced hand–foot skin reaction in a seropositive male _b: A rare presentation
250			_aVol.56(1), Jan-Feb
260			_aMumbai _bWolter Kluwer _c2024
300			_a55-57p.
520			_aHand–foot skin reaction (HFSR) is a specific but uncommon cutaneous side effect mainly following chemotherapeutic drugs such as multitargeted kinase inhibitors. HFSR is reversible and non-life-threatening. HFSR, also known as palmoplantar erythrodysesthesia, presents with various degrees of erythema, edema, hyperkeratosis, blister, and sometimes with a fine white scale. Dolutegravir, a first next-generation integrase inhibitor, is used with other antiretroviral therapy (ART) to treat mainly HIV infections. HFSR is diagnosed depending on the suggestive association of drug intake and characteristic palmoplantar eruption. ART can cause several cutaneous adverse drug reactions though no case report of dolutegravir-induced HFSR has been reported till date in literature. Here, we present a case of HFSR in a seropositive male on ART.
650		0	_94774 _aPHARMACOLOGY
700			_924747 _aBaisya, Subhasmita
773	0		_x0253-7613 _tIndian Journal of Pharmacology _dAndheri - Mumbai Wolters Kluwer India Private Limited
856			_uhttps://journals.lww.com/iphr/fulltext/2024/01000/dolutegravir_induced_hand_foot_skin_reaction_in_a.10.aspx _yClick here
942			_2ddc _cAR