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100			_926501 _aRasheed, Razia Abdul
245			_aEffect of glimepiride versus teneligliptin in combination with metformin in type 2 diabetes mellitus patients
250			_aVol.56(5), Sep-Oct
260			_aNew Delhi _bWolter Kluwer _c2024
300			_a317-321p.
520			_aBACKGROUND: Long-term metabolic disease type 2 diabetes mellitus (T2DM) is distinguished by elevated blood glucose, insulin resistance, and drought of insulin with dyslipidemia. Oral hypoglycemic agents lower blood glucose levels as well as prevent both short-term and long-term complications such as micro/macrovascular atherosclerosis, chronic kidney diseases, and chronic heart disease. This study aims to compare the effect of glimepiride versus teneligliptin in combination with metformin in T2DM patients attending a tertiary care hospital. MATERIALS AND METHODS: This prospective, randomized, open-label study was initiated in a tertiary care hospital after obtaining IEC approval. Written informed consent was obtained. The sample size was calculated using “Statistics and sample size software.” Ninety-seven patients satisfying the inclusion criteria were assigned to two groups using simple randomization with allocation 1:1. Group A received metformin + glimepiride while Group B received metformin + teneligliptin for 12 weeks. Fasting blood sugar (FBS), postprandial blood sugar (PPBS), glycated hemoglobin (HbA1c), and lipid profile were recorded at the baseline and at the end of 12 weeks. This study was conducted for 1 year. Data were analyzed using SPSS version 23.0 software.
650		0	_94774 _aPHARMACOLOGY
700			_926502 _aVenkatraman, G.
773	0		_x0253-7613 _dAndheri - Mumbai Wolters Kluwer India Private Limited _tIndian Journal of Pharmacology
856			_uhttps://journals.lww.com/iphr/fulltext/2024/09000/effect_of_glimepiride_versus_teneligliptin_in.3.aspx _yClick here
942			_2ddc _cAR