| 000 | a | ||
|---|---|---|---|
| 999 |
_c23445 _d23445 |
||
| 003 | OSt | ||
| 005 | 20250923115510.0 | ||
| 008 | 250923b xxu||||| |||| 00| 0 eng d | ||
| 040 |
_aAIKTC-KRRC _cAIKTC-KRRC |
||
| 100 |
_927143 _aGladwin, Evangeline |
||
| 245 |
_aExploring the clinical spectrum and individualized drug therapy in pemphigus vulgar is _b: a case series |
||
| 250 | _aVol.16(7) | ||
| 260 |
_aBhopal _bInnovare Academic Sciences Pvt Ltd _c2024 |
||
| 300 | _a54-57p. | ||
| 520 | _aPemphigus Vulgaris (PV) is a rare, chronic, life-threatening immunopathogenic disease that is characterized by flaccid, easily ruptured intraepithelial bullae, mostly found on the skin and mucous membranes. Attempting to keep the treatment plan of this potentially deadly disorder in primary focus, we have observed five patients with Pemphigus vulgaris. All patients have been presented with oral lesions or ulcers resulting in difficulty in swallowing. Patient one had a family history of the disease, while the other patients did not present any family history. All five patients had diverse ways of dealing with the disease before getting hospitalized. Microcytic anaemia and hypoalbuminemia have been found in all of them. Patients 1 and 3 had leucocytosis, while patient three had platelets in clumps with Hypercobalaminemia and the presence of ketone bodies in urine analysis. The Desmoglein I and Desmoglein III Antibody along with Punch biopsy results, confirmed the diagnosis. All patients were given systemic corticosteroids on hospitalization, but the case series observed variations in the dosages emphasizing individualized drug therapy. Some developed psychological impairment, some had generalized headaches or cardiac impairment, while ophthalmic involvement was seen in the other patients. Healthcare providers should do close monitoring while providing individualized drug therapy to prevent any systemic involvement and further complications. | ||
| 650 | 0 |
_94639 _aPHARMACEUTICS |
|
| 700 |
_927250 _aShah, Priyanshi |
||
| 773 | 0 |
_tInternational journal of pharmacy and pharmaceutical science _dBhopal Innovare Academic Sciences Pvt Ltd _x2656-0097 |
|
| 856 |
_uhttps://journals.innovareacademics.in/index.php/ijpps/article/view/51143 _yClick here |
||
| 942 |
_2ddc _cAR |
||