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040			_aAIKTC-KRRC _cAIKTC-KRRC
100			_aPawar, Rajesh Singh _927675
245			_aExploring the role of curcumin containing ethanolic extract obtained from Curcuma longa (rhizomes) against retardation of wound healing process by aspirin
250			_aVol.47(2), Mar-Apr
260			_aMumbai _bWolter Kluwer _c2015
300			_a160-166p.
520			_aThe aim of the study was to assess the curcumin containing ethanolic extract (EtOH) obtained from Curcuma longa (Cl) against retardation of wound healing by aspirin. Materials and Methods: Wound healing process was retarded by administering the dose of 150 mg/kg body weight of aspirin orally for 9 days to observe the effect of EtOH obtained from Cl using excision and incision wound model in rats. The various parameters such as % wound contraction, epithelialization period, hydroxyproline, tensile strength were observed at variant time intervals and histopathological study was also performed. Results: Curcumin containing 5% and 10% ethanolic extract ointment have shown significant (P < 0.01) wound healing activity against an aspirin (administered 150 mg/kg body weight orally for 9 days) retarded wound healing process. Topical application of ointment showed significant (P < 0.01) difference as compared to the control group. Histopathological studies also showed healing of the epidermis, increased collagen, fibroblasts and blood vessels.
650		0	_aPHARMACOLOGY _94774
700			_aToppo, Fedelic Ashish _927676
773	0		_tIndian Journal of Pharmacology _dAndheri - Mumbai Wolters Kluwer India Private Limited _x0253-7613
856			_uhttps://journals.lww.com/iphr/fulltext/2015/47020/exploring_the_role_of_curcumin_containing.6.aspx _yClick here
942			_2ddc _cAR
999			_c23722 _d23722