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040 _aAIKTC-KRRC
_cAIKTC-KRRC
100 _aKameshwari, J. S.
_927700
245 _aCase report on toxic epidermal necrolysis with etoricoxib
250 _aVol.47(2), Mar-Apr
260 _aMumbai
_bWolter Kluwer
_c2015
300 _a221-223p.
520 _aEtoricoxib is a selective cyclo-oxygenase 2 (COX-2) enzyme inhibitor and is exploited for its analgesic activity in various disease conditions like osteoarthritis, gouty arthritis, acute pain including postoperative dental pain and primary dysmenorrhea, etc. Although highly efficacious in pain management the safety profile of this COX-2 inhibitor is yet to be established in a broader sense. Short-term clinical trials and postmarketing surveillance have shown a very rare incidence of very serious skin reactions like Steven Johnson syndrome or toxic epidermal necrolysis (TEN). In this case report, we summarize regarding a patient who developed TEN after treatment with etoricoxib for osteoarthritis that later resolved in 15 days after withdrawal and symptomatic treatment.
650 0 _aPHARMACOLOGY
_94774
700 _aDevde, Raju
_927701
773 0 _tIndian Journal of Pharmacology
_x0253-7613
_dAndheri - Mumbai Wolters Kluwer India Private Limited
856 _uhttps://journals.lww.com/iphr/fulltext/2015/47020/a_case_report_on_toxic_epidermal_necrolysis_with.20.aspx
_yClick here
942 _2ddc
_cAR
999 _c23742
_d23742