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040			_aAIKTC-KRRC _cAIKTC-KRRC
100			_aKumari, Mrinalini _927728
245			_aTribulus terrestris ameliorates metronidazole-induced spermatogenic inhibition and testicular oxidative stress in the laboratory mouse
250			_aVol.47(3), May-Jun
260			_aMumbai _bWolter Kluwer _c2015
300			_a304-310p.
520			_aThe present study was undertaken to evaluate the protective effects of the fruit extract of Tribulus terrestris (TT) on the metronidazole (MTZ)-induced alterations in spermatogenesis, sperm count, testicular functions, and oxidative stress. Materials and Methods: Thirty adult Swiss strain mice were divided into six groups. Animals of Groups I and II served as untreated and vehicle-treated controls, while that of Groups III and IV were administered with MTZ (500 mg/kg BW/day) and TT (200 mg/kg BW/day) alone for 28 days, respectively. Low (100 mg/kg BW/day) and high (200 mg/kg BW/day) doses of TT along with MTZ (500 mg/kg BW/day) were administered for 28 days in the mice of Groups V and VI, respectively. Twenty four hours after the last treatment, all the animals were euthanized to study the histological changes in the testis and sperm count in the epididymis. Testicular functional markers, lipid peroxidation (LPO) and the activities of antioxidant enzymes, e.g., superoxide dismutase, catalase, glutathione peroxidase, and glutathione reductase, were also assessed in the mice of all the groups.
650		0	_aPHARMACOLOGY _94774
700			_aSingh, Poonam _921920
773	0		_x0253-7613 _dAndheri - Mumbai Wolters Kluwer India Private Limited _tIndian Journal of Pharmacology
856			_uhttps://journals.lww.com/iphr/fulltext/2015/47030/tribulus_terrestris_ameliorates.12.aspx _yClick here
942			_2ddc _cAR
999			_c23764 _d23764