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040			_aAIKTC-KRRC _cAIKTC-KRRC
100			_aMori, Miyu _927739
245			_aCase of early detection of bisphosphonate-related osteonecrosis of the jaw
250			_aVol.47(3), May-Jun
260			_aMumbai _bWolter Kluwer _c2015
300			_a334-335p.
520			_aOsteonecrosis of the jaws is an adverse reaction associated with the use of bisphosphonates. Although the diagnosis of bisphosphonate-related osteonecrosis of the jaw (BRONJ) is based on symptomatology, it is often detected late because the patients become symptomatic only after osteonecrosis is well established. We describe a case of early oral BRONJ detected by magnetic resonance imaging (MRI) accidentally. Head MRI revealed low signal of T1-weight images in left mandibula. Patient had been treated with minodronate for osteoporosis during 18 months. Based on the MRI findings and medication history, early stage BRONJ could be considered. Therefore minodronate was switched to teriparatide. Thereafter mandible pares-thesias, odontalgia and exposed bone were not observed. This case suggests that MRI is useful for the early detection of BRONJ.
650		0	_aPHARMACOLOGY _94774
700			_aKoide, Tetsuro _927740
773	0		_x0253-7613 _dAndheri - Mumbai Wolters Kluwer India Private Limited _tIndian Journal of Pharmacology
856			_uhttps://journals.lww.com/iphr/fulltext/2015/47030/a_case_of_early_detection_of.20.aspx _yClick here
942			_2ddc _cAR
999			_c23772 _d23772